INDEX 153
quantitative models of, 137-142
LPS. See Lipopolysaccharides
Lymphocytes, 54, 85, 96, 98, 100, 101,
105, 107, 109. See also specific
types
T. See T-cells
Lymphoreticular tissues, 96, 101
Macrophages, 96
Maturation time, 42
Menadione, 60
2- Mercaptoethanol, 15
Meta-analytic methods, 134-137
Metals, 41. See also specific types
Methylation, 45, 55
3- Methylcholanthrene, 63
Methylene chloride, 15, 25
O-Methylguanine, 54-55, 56
O-Methylguanine acceptor protein, 55
Methylmethanesulfonate (MMS), 55
Mirex, 64, 65
Mitogens, 105
MMS. See Methylmethanesulfonate
MNNG, 42
Modified linear multistage models,
140-141
Molecular biology, 43
Molecular models, 47
Mortality rates
age-specific, 1, 2, 4, 14
conditional. See Hazard function
first-order constant for, 2
instantaneous. See Hazard function
radiation dose and, 32
rate theory approach to, 2
Multistage models, 140-141
Mutagens, 46
Mutations, 114
Nalidixic acid, 45
Napierian logarithm of hazard
function. See Gompertz function
Neoteny, 11, 12
Neuroendocrinimmune system, 5
Newborn resilency, 76
Nonlinear least squares analysis, 3
Nuclear installations, 30-32
Nucleotides, 45. See also specific
types
Nutrients, 8, 53-56. See also specific
types
Oncogenes, 45, 55
“Overcorrection response,” 48
Oxidation by-products, 5
Oxidation stress response, 45
Oxidizing agents, 41
Oxygen metabolism, 5
Oxygen poisoning, 41
Oxygen species, 44
Oxy R response, 44
P-450. See Cytochrome P-450
Partial hepatectomy, 73, 74
Peppermint, 3
Peroxides, 5
Pesticides, 61. See also specific types
PHA. See Phytohemagglutinin
Pharmacologic agents, 9, 10. See also
specific types
Phenobarbital, 47, 60, 63, 64, 65, 71,
72, 80
Phosfon, 3
Phosphorylase a, 67, 71
Phosphorylase b, 71
Photomirex, 64, 65
Photoreactivation, 41
Physical activity, 9
Physiologically abnormal behavior,
115
Physiological view of carcinogenesis,
115-117
Phytohemagglutinin (PHA), 105, 110
Plasma membrane, 44
Poly ADP-ribose, 45
Polychlorinated biphenyls, 41, 63. See
also specific types
Premature infants, 12
Preventable disease, 6
Prevention of injury, 59, 60
Procaine, 15, 44
Proliferation of cells, 81
Propagation of lipid peroxidation, 61
Proteases, 45
Proteins, 44. See also specific types
chromosomal, 46
degradation of abnormal, 46
heat shock, 43-44, 46, 47