Devita, Hellman, and Rosenberg's Cancer

LWBK1006-22 LWW-Govindan-Review December 12, 2011 19:7

CHAPTER 22 CANCER OF

THE TESTIS

SAIAMA WAQAR•DANIEL MORGENSZTERN•BRUCE ROTH

DIRECTIONS Each of the numbered items below is followed by lettered answers. Select the

ONE lettered answer that is BEST in each case unless instructed otherwise.

QUESTIONS

Question 22.1. Which germ cell tumor is associated with widespread hematogenous

metastases and high levels of human chorionic gonadotropin (HCG)?

A. Pure choriocarcinoma

B. Yolk sac tumor

C. Embryonal carcinoma

D. Seminoma

Question 22.2. Which of the following is associated with primary nonseminomatous

mediastinal germ cell tumors?

A. Human immunodeficiency virus (HIV)

B. Klinefelter syndrome

C. Diethylstilbestrol exposure

D. None of the above

Question 22.3. Which of the following is a risk factor for central nervous system involve-

ment in patients with testicular cancer?

A. Large volume pulmonary metastases

B. Pure choriocarcinoma histology

C. HCG>100,000

D. All of the above

Question 22.4. Which immunohistochemical markers are commonly expressed in

patients with seminoma?

A. CD117

B. Placental alkaline phosphatase (PLAP)

C. None of the above

D. A and B

Corresponding Chapter inCancer: Principles & Practice of Oncology,Ninth Edition: 99 (Cancer of the Testis).

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