Devita, Hellman, and Rosenberg's Cancer

LWBK1006-23 LWW-Govindan-Review December 12, 2011 19:10

330 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

led to dramatic overtreatment and loss of fertility (hysterectomy) for some

patients. If phantom hCG is suspected, urine hCG should be obtained. The

heterophile antibodies are not present in the urine, and this test should

be negative.

Answer 23.2.37. The answer is C.

Treatment for GTN is based on risk assessment either by the WHO or the

FIGO guidelines. Low-risk disease is typically treated with methotrexate

or actinomycin-D. Treatment is continued until the hCG levels are normal

for 3 consecutive weeks. The patient is then followed monthly for 12

months. Hysterectomy can be offered for patients who have completed

childbearing.