LWBK1006-24 LWW-Govindan-Review December 12, 2011 19:15
334 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology ReviewQuestion 24.16. The use of radiation therapy (RT) after lumpectomy in patients with
DCIS:
A. Improves overall survival (OS)
B. Reduces the risk of recurrent DCIS, but not invasive disease, in the
treated breast
C. Does not decrease local recurrence when tamoxifen therapy is admin-
istered
D. None of the aboveQuestion 24.17. Which of the following are pathologic subtypes of breast cancer associated
with a more favorable prognosis?
A. Metaplastic
B. Scirrhous
C. Tubular
D. MedullaryQuestion 24.18. What stage describes a patient with a 3 cm primary breast tumor
metastatic to a movable ipsilateral lymph node?
A. T1N1M0 (IIA)
B. T2N1M0 (IIA)
C. T2N1M0 (IIB)
D. T3N1M0 (IIB)Question 24.19. For which of the following there is insufficient evidence to recommend
annual MRI screening?
A. BRCAmutation
B. Radiation to the chest between ages 10 and 30
C. First-degree relatives of Cowden syndrome
D. Personal history of breast cancerQuestion 24.20. Which of the following patients is at greatest risk of local recurrence after
breast-conserving therapy?
A. A 65-year-old with a 2-cm grade 1, ER+tumor, closest margin 3 mm,
treated with whole breast radiation therapy (WBRT) (no boost), and
an aromatase inhibitor (AI)
B. A 25-year-old with a 2-cm grade 3, ER – tumor, closest margin
<1 mm, treated with WBRT (with boost) and no systemic therapy
C. A 35-year-old with a 2-cm grade 2, ER – tumor, closest margin 6 mm,
treated with WBRT (with boost) and adjuvant chemotherapy
D. A 65-year-old with a 4-cm grade 1, ER+tumor, closest margin 4 mm,
treated with WBRT (with boost) and an AIQuestion 24.21. Which of the following is an absolute contraindication to breast-
conserving surgery (BCS)?
A. Two or more primary tumors in separate quadrants
B. Collage vascular disease
C. Large tumor in a smaller breast
D. Primary tumor size of 4.8 cm