Devita, Hellman, and Rosenberg's Cancer

LWBK1006-30 LWW-Govindan-Review December 12, 2011 19:35

414 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

Question 30.4. All of the following inherited syndromes are associated with a higher risk

of childhood lymphomas, EXCEPT:

A. Wiskott-Aldrich

B. X-linked lymphoproliferative syndrome

C. Ataxia telangiectasia

D. Human immunodeficiency virus (HIV)-acquired immunodeficiency

syndrome (AIDS)

Question 30.5. The following are true regarding anaplastic large cell lymphomas,

EXCEPT:

A. Primary systemic ALCL often have at(2;5)(p23;q35).

B. Prognosis in ALK-positive cases is worse than in ALK negative.

C. ALK protein is detected in the majority of cases.

D. ALK-positive cases are most common in children.

Question 30.6. Which B-cell malignancy is associated with the highest percentage of

patients with Ann Arbor stage IV:

A. Follicular lymphoma.

B. Burkitt’s lymphoma.

C. Small lymphocytic lymphoma (SLL)

D. Mantle cell lymphoma (MCL)

Question 30.7. Regarding the epidemiology of lymphoma, all of the following are true,

EXCEPT:

A. Non-Hodgkin’s lymphoma (NHL) and HL are the most commonly

occurring hematologic malignancies in the United States and the fifth

leading cause of cancer death in the United States.

B. Nasal T-cell lymphomas are more common in China.

C. The largest increases have occurred in low-grade lymphomas.

D. Higher rates of gastric lymphoma have been reported in Northern

Italy.

Question 30.8. Which of the following is not a poor risk factor in the International Prog-

nostic Index (IPI)?

A. Age> 60

B. Ann Arbor stage IV

C. Hemoglobin 10

D. Performance status (PS) 3

Question 30.9. Which of the following diseases is caused by human herpesvirus-8?

A. Castleman’s disease.

B. Burkitt’s lymphoma

C. Monocytoid B-cell lymphoma

D. A and C