Tissue Engineering And Nanotheranostics

“9.61x6.69” b2815 Tissue Engineering and Nanotheranostics

Magnetic Nanohybrids for Magnetic Resonance Imaging 111

salt FeCl 2.^ 4H 2 O with PEI/Ag complex. Subsequently, gold growth

solution was obtained using HAuCl 4 in CTAB, AgNO 3 (1.1 mg) and

ascorbic acid. After Fe 3 O 4 /Ag solution was introduced to the above

gold growth solution to fabricate MAu–NSs, partially thiolated PEI

(PEI–SH) was used to enhance the surface properties and biocom-

patibility as shown in Fig. 5(a). Figures 5(b) and 5(c) illustrates the

TEM pictures of MAu–NSs magnetic plasmonic nanohybrid struc-

ture at low and high magnification. After the formation of gold leaves

onto the surface of magnetic nanoparticles, an obvious plasmon reso-

nance peak of Au appears in the 550–850 nm regions.^38 This method

is also applied to fabricate manganese-doped iron oxide@gold core–

shell hybrid structure. Gao et al. reported an advanced generation of

magnetic–plasmonic core–shell hybrid nanocrystals by producing a

gap between core and shell as shown in Figs. 5(d) and 5(e).^37

Hydophobic small magnetic particles synthesized using thermal

Fig. 5. (a) Schematic representation and (b),(c) TEM picture at low and high
magnification of magnetic-gold nanostars (MAuNSs) like nanohybrid structure.
(d) Graphic representation of magnetic-gold core–shell Nanoparticles and (e) TEM
pictures of monodispersed hydrophobic MNPs coated with gold. Reprinted with
permission from Refs. 35 and 37.