b2815 Tissue Engineering and Nanotheranostics “9.61x6.69”34 Tissue Engineering and Nanotheranostics
implantation showed a reduction in total surface area with an average
shrinkage of 14 ± 10% for Optilene® LP against 25 ± 6% for INFINIT®,
which was significant (p = 0.017).^12 The maximum reduction in
length and width was 1.2 cm and 1.0 cm, respectively for Optilene®
LP, and 2.0 cm and 1.0 cm, respectively for INFINIT®.^12
This study also establishes the relationship between mesh weight
and inflammatory response. In case of patches used for fetal surgeries
such as MMC repair, the patch weight would be of great importance
not only due to inflammatory response but also due to the possibility
of a negative effect on the growth of fetus. Hence, the optimal
weight of a surgical patch needs to be studied further for fetal
research.
2.2. Mechanical Properties
Mechanical properties of surgical patches are of primary importance,
since they impart requisite virtues such as elasticity, stiffness, long-term
durability, strength and modulus. Fatigue failure or deformation of an
Fig. 3. Boxplots showing shrinkage rate for Optilene® LP and INFINIT® meshes.^120.350.300.250.20shrinkage (x/1)0.150.100.050.00
Optilene® LP Infinit®