Microfluidics for Biologists Fundamentals and Applications

work. This technology has very prominent advantage with respect to low overall chip area and high integration density. For handl ...

and thus promotes low cost clinical diagnostics which can be of immense utility in resource poor settings. Various advantages th ...

source (Fig.2.1). In this process, the key is the photon having exactly the same wavelength as that of the emitted light [ 4 ]. ...

of reactive species during the laser ablation process which makes this process very attractive to biological assays. Laser fabri ...

2.2 Photo-Lithography Photo lithography is a non-contact process which deploys the power of light exposure to print extremely sm ...

2.2.2 Alignment Pattern alignment plays a major role in photo-lithography for making controlled feature sizes and shapes. The pa ...

2.2.3 Exposure The main exposure parameters to achieve accurate pattern transfer from the mask to the photosensitive layer depen ...

2.4 Micro-Scale Replication by Double Inversion (MRDI) Process Biological and chemical applications require micro-fluidic device ...

The principle advantages offered by the MRDI process are: (1) a sturdy mold, (2) repeated use of the mold for replication of pol ...

realize high aspect ratio micro-channels, thin wires of copper etched to a diameter of 50–80μm were inserted between opposing ho ...

There are many other soft lithography approaches which have been reported in literature like solvent assisted micromoulding, nan ...

angular orientations in respect of the flow direction. Various strategies have been developed for micro-mixing which has been br ...

T-type or Y-type micromixers and also parallel and sequential Lamination mixer [ 34 ]. Nanoparticle synthesis using microscale c ...

damping. The channel array is embedded in blocks of viscoelastic materials in an oil filled and hermetically sealed manner [ 27 ...

3.4 Micro-pump Micro-pump are MEMS based fluid handling devices which again work passively or actively to initiate flow through ...

off. At frequencies more or equal to 50 Hz, no pumping action was observed which was attributed to viscosity of the pumped fluid ...

membrane thus reducing the problem of fluid retainability inside the chambers. Figure2.13shows optical micrograph of pumping cha ...

3.5 Micro-valve Micro-valves are designed to control the switching action of flows in microchannels. This helps in controlling t ...

through Field Emission Scanning Electron Microscopy (FESEM) and thin wafers of the gel were physically placed inside PDMS microc ...

Both micro-cantilevers as well as other three-dimensional micro-structures have been exclusively used for sensing and diagnostic ...