215- Pedrosa RP, Drager LF, Gonzaga CC, Sousa MG, de Paula LKG, Amaro ACS, et al. Obstructive
sleep apnea: the most common secondary cause of hypertension associated with resistant
hypertension. Hypertension. 2011;58(5):811–7. - Walia HK, Li H, Rueschman M, Bhatt DL, Patel SR, Quan SF, et al. Association of severe
obstructive sleep apnea and elevated blood pressure despite antihypertensive medication use.
J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med. 2014;10(8):835–43. - Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, et al. Resistant hypertension:
diagnosis, evaluation, and treatment a scientific statement from the American Heart Association
Professional Education Committee of the Council for high blood pressure research. Circulation.
2008;117(25):e510–26. - Tobias L. “PocketDoktor” patient information booklet on Obstructive Sleep Apnea, 2014, Pelz
Verlag GmbH, Germany. - Parati G, Ochoa JE, Bilo G, Mattaliano P, Salvi P, Kario K, et al. Obstructive sleep apnea syn-
drome as a cause of resistant hypertension. Hypertens Res Off J Jpn Soc Hypertens.
2014;37(7):601–13. - Foster GE, Brugniaux JV, Pialoux V, Duggan CTC, Hanly PJ, Ahmed SB, et al. Cardiovascular
and cerebrovascular responses to acute hypoxia following exposure to intermittent hypoxia in
healthy humans. J Physiol. 2009;587(Pt 13):3287–99. - Tamisier R, Pépin JL, Rémy J, Baguet JP, Taylor JA, Weiss JW, et al. 14 nights of intermittent
hypoxia elevate daytime blood pressure and sympathetic activity in healthy humans. Eur
Respir J. 2011;37(1):119–28. - Tkacova R, McNicholas WT, Javorsky M, Fietze I, Sliwinski P, Parati G, et al. Nocturnal inter-
mittent hypoxia predicts prevalent hypertension in the European Sleep Apnoea Database
cohort study. Eur Respir J. 2014;44(4):931–41. - Friedman O, Bradley TD, Chan CT, Parkes R, Logan AG. Relationship between overnight
rostral fluid shift and obstructive sleep apnea in drug-resistant hypertension. Hypertension.
2010;56(6):1077–82. - Gaddam K, Pimenta E, Thomas SJ, Cofield SS, Oparil S, Harding SM, et al. Spironolactone
reduces severity of obstructive sleep apnoea in patients with resistant hypertension: a prelimi-
nary report. J Hum Hypertens. 2010;24(8):532–7. - Sharma AM, Wittchen H-U, Kirch W, Pittrow D, Ritz E, Göke B, et al. High prevalence and
poor control of hypertension in primary care: cross-sectional study. J Hypertens.
2004;22(3):479–86. - Rasche K, Keller T, Tautz B, Hader C, Hergenç G, Antosiewicz J, et al. Obstructive sleep apnea
and type 2 diabetes. Eur J Med Res. 2010;15(Suppl 2):152–6. - American Academy of Sleep Medicine. International Classification of Sleep Disorders. 3rd ed.
Darien: American Academy of Sleep Medicine; 2014. - Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, et al. Rules for scoring respi-
ratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associ-
ated events. Deliberations of the sleep apnea definitions task force of the American Academy
of Sleep Medicine. J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med. 2012;
8(5):597–619. - Myers KA, Mrkobrada M, Simel DL. Does this patient have obstructive sleep apnea?: the
rational clinical examination systematic review. JAMA. 2013;310(7):731–41. - Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale.
Sleep. 1991;14(6):540–5. - Ramachandran SK, Josephs LA. A meta-analysis of clinical screening tests for obstructive
sleep apnea. Anesthesiology. 2009;110(4):928–39. - Qaseem A, Dallas P, Owens DK, Starkey M, Holty J-EC, Shekelle P. Diagnosis of obstructive
sleep apnea in adults: a clinical practice guideline from the American college of physicians
diagnosis of obstructive sleep apnea in adults. Ann Intern Med. 2014;161(3):210–20.
13 Obstructive Sleep Apnea and Resistant Hypertension