BNF for Children (BNFC) 2018-2019

TABLE 12

Drugs that cause peripheral neuropathy The following is a list of some drugs that cause peripheral neuropathy (note that this list is not exhaustive). Concurrent use of two or more drugs from the list might increase this risk.

amiodarone bortezomib brentuximab vedotin cabazitaxel cisplatin

didanosine disulfiram docetaxel eribulin fosphenytoin

isoniazid lamivudine metronidazole nitrofurantoin paclitaxel

phenytoin stavudine thalidomide vinblastine vincristine

vindesine vinflunine vinorelbine

TABLE 13

Drugs that cause serotonin syndrome The following is a list of some drugs that cause serotonin syndrome (note that this list is not exhaustive). See’Serotonin Syndrome’and ’Monoamine-Oxidase Inhibitors’underAntidepressant drugsp. 235 for more information and for specific advice on avoiding monoamine- oxidase inhibitors during and after administration of other serotonergic drugs.

almotriptan bupropion buspirone citalopram clomipramine dapoxetine dexamfetamine duloxetine eletriptan escitalopram

fentanyl fluoxetine fluvoxamine frovatriptan granisetron imipramine isocarboxazid linezolid lisdexamfetamine lithium

methadone methylthioninium chloride mianserin mirtazapine moclobemide naratriptan ondansetron palonosetron paroxetine pentazocine

pethidine phenelzine procarbazine rasagiline rizatriptan safinamide selegiline sertraline St John’sWort sumatriptan

tapentadol tramadol tranylcypromine trazodone tryptophan venlafaxine vortioxetine zolmitriptan

TABLE 14

Antidiabetic drugs The following is a list of antidiabetic drugs (note that this list is not exhaustive). Concurrent use of two or more drugs from the list might increase the risk of hypoglycaemia.

acarbose albiglutide alogliptin canagliflozin dapagliflozin

dulaglutide empagliflozin exenatide glibenclamide gliclazide

glimepiride glipizide insulins linagliptin liraglutide

lixisenatide metformin nateglinide pioglitazone repaglinide

saxagliptin sitagliptin tolbutamide vildagliptin

TABLE 15

Drugs that cause myelosuppression The following is a list of some drugs that cause myelosuppression (note that this list is not exhaustive). Concurrent use of two or more drugs from the list might increase this risk.

afatinib aflibercept alemtuzumab amsacrine anakinra arsenic trioxide asparaginase axitinib azacitidine azathioprine balsalazide belimumab bendamustine bevacizumab bleomycin blinatumomab bortezomib bosutinib brentuximab vedotin busulfan cabazitaxel cabozantinib canakinumab capecitabine carbimazole carboplatin carfilzomib

carmustine ceritinib cetuximab chlorambucil cisplatin cladribine clofarabine clozapine co-trimoxazole crisantaspase crizotinib cyclophosphamide cytarabine dabrafenib dacarbazine dactinomycin dasatinib daunorubicin decitabine deferiprone docetaxel doxorubicin epirubicin eribulin estramustine ethosuximide etoposide

everolimus fludarabine fluorouracil ganciclovir gefitinib gemcitabine hydroxycarbamide ibrutinib idarubicin idelalisib ifosfamide imatinib interferon alfa interferon beta irinotecan leflunomide lenalidomide linezolid lomustine melphalan mercaptopurine methotrexate mitomycin mitotane mitoxantrone mycophenolate nelarabine

nilotinib nivolumab obinutuzumab ofatumumab olanzapine olaparib olsalazine oxaliplatin paclitaxel panitumumab panobinostat pazopanib pegaspargase peginterferon alfa peginterferon beta-1a pemetrexed pentamidine pentostatin pixantrone pomalidomide primaquine procarbazine propylthiouracil pyrimethamine raltitrexed ramucirumab regorafenib

rituximab ruxolitinib siltuximab sorafenib sulfadiazine sulfasalazine sunitinib temozolomide temsirolimus thalidomide thiotepa tioguanine topotecan trabectedin trastuzumab emtansine treosulfan valganciclovir vinblastine vincristine vindesine vinflunine vinorelbine vismodegib zidovudine

850 Appendix 1 Interactions BNFC 2018 – 2019

Interactions

|Appendix 1

A1

BNF for Children (BNFC) 2018-2019

TABLE 12

TABLE 13

TABLE 14

TABLE 15

Get our desktop app

Company

Features

Documentation

Resources