Medical Microbiology

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Table 1 2. 2 Continued:LowerRespiratoryTract

Infection Mostimportant
pathogens

Laboratorydiagnosis

Pulmonaryhantaviruses
(USA)

Serology

Enteroviruses Isolationfrompharyngeal
lavageorbronchial
secretion
Rhinoviruses Laboratorydiagnosisnot
recommended
Bacteria(80– 90 %)
“Community-acquired
pneumonia”

Streptococcuspneumoniae
(30%)
Haemophilusinfluenzae(5%)
Staphylococcusaureus(5%)
Klebsiellapneumoniae
Legionellapneumophila
Mixedanaerobicflora
(aspirationpneumonia)

Microscopyandculturing
fromexpectorated
sputum,orbetteryetfrom
transtrachealorbronchial
aspirate,frombronchoalveolar
lavageorbiopsymaterial.
Ifanaerobesaresuspected
usespecialtransportvessels
Mycoplasmapneumoniae
(1 0 %)
Coxiellaburnetii
Chlamydiapsittaci

Serology

Serology
Serology:CFTcandetect
onlyantibodiestogenus.
Microimmunofluorescence
(MIF)species-specific
Chlamydiapneumoniae Serology:MIF
“Hospital-acquired
pneumonia”

Enterobacteriaceae
Pseudomonasaeruginosa
Staphylococcusaureus

Laboratoryprocedures
seeaboveat“community-
acquiredpneumonia”
Fungi Aspergillusspp.
Candidaspp.
Cryptococcusneoformans
Histoplasmacapsulatum
Coccidioidesimmitis
Blastomycesspp.
Mucorales

Microscopyandculture,
preferablyfromtranstracheal
orbronchialaspirate,
bronchoalveolarlavageor
lungbiopsy.Serologyoften
possible
(seeChapter5)

LowerRespiratoryTract 633

12

Kayser, Medical Microbiology © 2005 Thieme

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