There is also no scientific evidence to suggest that diet
can detoxify the body.
There has been some concern about the supple-
ments that are required or recommended for the Mak-
er’s diet program. These supplements are made by
Rubin’s company Garden of Life, Inc. In a letter
dated May 11, 2004 the United States Food and
Drug Administration ordered the company to stop
making unsubstantiated claims about eight of its
products and supplements. The claims were made in
brochures, on labels, and in Rubin’s bookPatient
Heal Thyself.
Resources
BOOKS
Rubin, Jordan.Patient Heal Thyself.Topanga, CA: Free-
dom Press, 2003.
Rubin, Jordan.The Great Physician’s RX for Chronic
Fatigue and Fibromyalgia.Nashville, TN: Thomas
Nelson, 2007.
Rubin, Jordan.The Maker’s Diet.New York: Penguin,
2005.
BOOKS
Shannon, Joyce Brennfleck ed.Diet and Nutrition Source-
book.Detroit, MI: Omnigraphics, 2006.
Willis, Alicia P. ed.Diet Therapy Research Trends.New
York: Nova Science, 2007.
PERIODICALS
Maslin, Janet. ‘‘The Plot Is Simple: Sell Books’’New York
Times(3 March 2004): V153 I52800 E33.
ORGANIZATIONS
American Dietetic Association. 120 South Riverside Plaza,
Suite 2000, Chicago, Illinois 60606-6995. Telephone:
(800) 877-1600. Website:<http://www.eatright.org>
OTHER
The Maker’s Diet2005.<http://www.makersdiet.com>
(April 7, 2007).
Helen M. Davidson
Manganese
Definition
Manganese (Mn) is a mineral necessary in very
tiny (trace) amounts for human health. In large quan-
tities, manganese is poisonous. Manganese is used in
some enzyme reactions and for the proper develop-
ment of bones and cartilage. Humans must meet their
needs for manganese from their diet. Manganese is
found mainly in plants and in small quantities in
some drinkingwater.
Purpose
Researchers understand less about how manga-
nese functions in the body than they do about many
otherminerals. Studies have shown that manganese is
necessary for proper development of healthy bones
and cartilage in animals. It is highly likely that man-
ganese plays the same role in the development of
human bones and connective tissue, although manga-
nese deficiency is so rare in humans (and putting peo-
ple on a prolonged manganese-free diet would be an
unethical experiment) that this has not been proven
experimentally.
Manganese is also necessary for the formation of
an antioxidant enzyme in cellular mitochondria. Mito-
chondria, sometimes called the cell’s power plant, are
organelles that use large amounts of oxygen to pro-
duce energy. The production of energy by the mito-
chondria results in the formation of free radicals. Free
Manganese
Recommended Dietary Tolerable Upper
Age Allowance (mg) Intake Level (mg)
Children 0–6 mos. 0.3 (AI) Not established
Children 7–12 mos. 0.6 (AI) Not established
Children 1–3 yrs. 1.2 2
Children 4–8 yrs. 1.5 3
Boys 9–13 yrs. 1.9 6
Girls 9–13 yrs. 1.6 6
Boys 14–18 yrs. 2.2 9
Girls 14–18 yrs. 1.6 9
Men 19 yrs. 2.3 11
Women 19 yrs. 1.8 11
Pregnant women 2.0 11
Breastfeeding women 2.6 11
Food Manganese (mg)
Tea, green, 1 cup 1.58
Pineapple, raw, ½ cup 1.28
Pecans, 1 oz. 1.12
Cereal, raisin bran, ½ cup .94
Brown rice, cooked, ½ cup .88
Spinach, cooked, ½ cup .84
Tea, black, 1 cup .77
Almonds, 1 oz. .74
Bread, whole wheat, 1 slice .65
Peanuts, 1 oz. .59
Sweet potato, mashed, ½ cup .55
Beans, navy, cooked, ½ cup .51
Beans, lima, cooked, ½ cup .48
Beans, pinto, cooked, ½ cup .48
AI Adequate Intake
mg milligram
(Illustration by GGS Information Services/Thomson Gale.)
Manganese