SPACE TISSUE LOSS (STL), FIVE INVESTIGATIONS
Research Area: Cellular Biology
Expedition(s): 23 and 24, 27 and 28
Principal Investigator(s): ● Rasha Hammamieh, PhD, United States Army, Ft Detrick,
Maryland
● Cheryl A. Nickerson, PhD, Arizona State University, Tempe,
Arizona
● Eduardo Almeida, PhD, Ames Research Center, Moffett Field,
California
● Eduardo Almeida, PhD, Ames Research Center, Moffett Field,
California
● H. Joon Paek, PhD, Tissue Genesis, Inc, Honolulu, Hawaii
RESEARCH OBJECTIVES
STL-MRMC (HAMMAMIEH)
Space Tissue Loss is a
Department of Defense
(DoD) Space Test Program
payload flying both DoD and
NASA science using cell and
tissue cultures in
microgravity to study the
effects of tissue regeneration
and wound healing in space.
STL-MICROBIAL IMMUNITY
(NICKERSON)
Space Tissue Loss - Microbial
Immunity (STL-Microbial
Immunity) is a Department of
Defense Space Test Program payload examining how human cells respond to bacterial
infections in space and if normal processes seen on Earth occur in the space environment. This
experiment could yield valuable knowledge leading to advances in vaccine development and
other therapeutics for treatment, prevention, and control of infectious diseases on Earth.
STL-REGENERATION (ALMEIDA)
Space Tissue Loss - Stem Cell Regeneration (STL-Regeneration) is a Department of Defense
Space Test Program payload studying stem cell regeneration in mouse cell culture in
microgravity examining the effects of tissue regeneration in space. Cell culture in microgravity
serves as a model system for understanding necrosis of tissue following severe injuries on
Earth.
Pilot Jeffrey S. Ashby works with the Space Tissue Loss-B middeck
experiment locker.