COMPREHENSIVE STUDY OF THE PATTERN OF MAIN INDICATORS OF CARDIAC
ACTIVITY AND BLOOD CIRCULATION (CARDIO-ODNT/CARDIO-ODNT PERFECTION), TWO
INVESTIGATIONS
Research Area: Cardiovascular and Respiratory Systems
Expedition(s): 1, 2, 4, 6, 7, 10, 12, 14- 17
Principal Investigator(s): ● Valeriy V. Bogomolov, PhD, Institute of Medical and Biological
Problems of the Russian Academy of Sciences, Moscow, Russia
RESEARCH OBJECTIVES
Comprehensive Study of the Pattern of Main Indicators of Cardiac Activity and Blood Circulation
(Cardio-ODNT/Cardio-ODNT Perfection) identifies the associations in regulation of human
systemic and pulmonary circulation during the stages of individual adaptation to conditions of
long-term microgravity using functional load testing along with the application of negative
pressure to the lower part of the body (LBNP) in order to assess and predict orthostatic
intolerance (dizziness upon standing up).
EARTH BENEFITS
The scientific results of the Cardio-ODNT
experiment are intended for doctors working
mainly on the medical support of manned
spaceflights. New knowledge is expected to be
the major benefit of this investigation.
SPACE BENEFITS
The adaptation mechanisms of various levels of
the human circulatory system in microgravity
can be clarified from studying the functional
capabilities of the human body in spaceflight.
The scientific information obtained make it
possible to analyze and evaluate the functional
state of the cardiovascular system overall, and
in particular the filling capacity and tone of
blood vessels of various sizes in each region
tested in accordance with criteria generally
accepted in normal clinical practice, including
determining functional state ranges (high,
normal, and low blood pressure, high and low
blood volume). Results from this study adds
substantially to the knowledge of the impact of microgravity on the functional state of various
parts of the cardiovascular system of crew members in long-term spaceflights.
RESULTS
Objective information was obtained for the first time enabling the functional state of various
regions of the systemic and the pulmonary circuit to be comprehensively evaluated with LBNP
Cosmonaut Sergey Volkov performs the Cardio-
ODNT experiment. Roscosmos image.