Medicinal Chemistry

sphingomyelin, 472
spirolactone, 337
spongiform encephalopathy, 514
spongiform vacuolation, 514
squalene epoxidase, 582
SS, 339, 340, 343–345
SSRI, 238
stanozolol, 329
Staphylococcus aureus,27
starch, 528
Starling, 310
statins, 318
status epilepticus, 8, 31, 422
staurosporine, 457, 458
stavudine, 555
steran, 312, 314
stereochemistry, 36–39
stereoisomeric bile acids, 316
Sternbach, Leo, 274
steroid hormone receptors, 312–314
steroid hormones, 312–337
biosynthesis, 315–316
structure, 314–315
steroid sparing agents, 394
steroids, 474
stomach, pH, 13
streptomycin, 477, 574
stroke, 286–288, 293, 294, 317, 379
strychnine, 282
subarachnoid hemorrhage, 427
substance P, 291, 339
substantia nigra, 199, 239
subthalamus, 199
succinylcholine, 18, 155, 156, 215
sucralfate, 269
sucrose, 476
suicide inhibitors, 484, 485–486
suicide substrates, 485
sulfa antibiotics, 577–580
sulfamethoxine, 579
sulfanilamide, 578
sulfasalazine, 149
sulfathiazole, 579
sulfentanil, 358
sulfisoxazole, 579
sulfonamide, 16
sulfonamide metabolism, 152
sulfonation, 181
sulfonic acids, 152
sulindac, 525
sulonylureas, 367
sumatriptan, 18, 260
sympathetic nervous system, 203
synapse, 194–196
syntheses, drug molecules, 128–130

synthon method, 129

α-synuclein, 514

systemic lupus erythmatosus, 395, 404, 405

systolic pressure, 378

T 3 , 360, 361

T 4 , 360, 361

tachycardia, 420

tacrolimus, 395

TAF1, 325

TAF2, 325

Taft parameter, 36

tamoxifen, 161, 324, 325, 347, 458, 537

tandamine, 241

tangle, 515

tapeworm, 585

tardive dyskinesia, 246

tau protein, 514, 515

taurine, 296–297

tazobactam, 556

TBG, 360

TBPA, 360

tegmentum, 199

temazepam, 275

temporal lobe, 201

tenoxicam, 525

teprotide, 373–376

teratogenesis, 161

terazosin, 231

terbinafine, 584

terbutaline, 233

terfenadine, 266

teriparatide acetate, 364

terpenes, 473–474

terpenoids, 474

tertiary structure, peptide, 466

testosterone, 329

testosterone propionate, 330

tetany, 424

tetracaine, 417

tetracycline, 121, 161, 573–574

tetraethylammonium, 415

tetrahydrocannabiol, 258

tetraiodothyroxine, 360

tetrodotoxin, 414

thalamus, 199

thalidomide, 394–396

THC, 258

thecal sac, 201

theophylline, 14, 16, 18

therapeutic index, 77

thiabendazole, 591

thiamine, 504

thiazolidinediones, 367, 369

thienamycin, 568

INDEX 647