Emergency Medicine

38 Critical Care Emergencies

Drug

Loading dose

Paediatric infusion

Dilution

Adult dose (70–80 kg)

range (< 30 kg)

Infusion pu

mp (IP)

Syringe driver

Concentration

Dose per hour

Volu

me per hour

Octreotide

50–200 μg

3–5 μg/kg/h

1000 μg in

500 μg in

10 μg/mL

25–100 μg/h

2.5–10 mL/h

100 mL DS

50 mL DS

Phenobarbitone

15–25 mg/kg in

—

—

—

—

—

—

(phenobarbital)

100 mL DS over 20–30 min (max. 50 mg/min) by IP

Phenytoin

15–18 mg/kg in

—

—

—

—

—

—

100 mL NS over 20–30 min (max. 50 mg/min) by IP

Procainamide

10 mg/kg (max.

20–80 μg/kg/min

1000 mg in

500 mg in

10 mg/mL

2–6 mg/min

12–36 mL/h

1000 mg) in

100 mL DW

50 mg DW

100 mL DW over 30 min by IP

Propofol

Sedation: 1–10 mg/kg/h

—

500 mg in 50 mL

10

mg/mL

Sedation Sedation

0.5–1.0 mg/kg

(dispensed as

1–2 mg/kg/h

7–15 mL/h

Induction: 20-mL and

Anaesthesia

Anaesthesia

2–3 mg/kg

50-mL amps,

5–10 mg/kg/h

35–70 mL/h

both with 10 mg/mL)