Emergency Medicine

Critical Care Emergencies 39

rt-PA

(alteplase)

15-mg bolus (15 ml)

—

100 mg in

—

1 mg/ml

(a) 15-mg bolus

100 ml water BP

(b) 0.75 mg/kg(max 50 mg)over 30 min(c) 0.5 mg/kg(max 35 mg)over 60 min

r-PA

(reteplase)

10-U bolus in

—

—

2 vials/prefilled

2 min. After 30 min,

syringes/

second 10-U

reconstitution

bolus in 2 min

devices andneedles

Salbutamol

5–10 μg/kg in 100 ml

1.0–5.0 μg/kg/min

6 mg in

3 mg in

60 μg/ml

5–50

μg/min

5–50 ml/h

(asthma)

DS over 10 min

100 ml DS

50 ml DS

Salbutamol

5–10 μg/kg in 100 ml

0.2–1.0 μg/kg/min

6 mg in

3 mg in

60 μg/ml

10–50

μg/min

10–50 ml/h

(obstetric)

DS over 10 min

100 ml DS

50 ml DS

Sodium

—

0.05–10 μg/kg/min

100 mg in 500 mL

—

Min 200

0.05–10 μg/kg/min

1–210 mL/h

nitroprusside

DW in glass bottle

μg/mL

(max. 1.5 mg/kg/24h)

500 mL/24h

Protect from light

Max 800

Discard at 24 h

μg/min

Streptokinase

1.5 million units in

—

—

—

15 000

2.5 mL/min

150 mL/h

AMI

100 mL NS over

units/mL

45 min by IP

PE, DVT, etc.

250 000 units in

1500–2000

500 000 units in

—

5000 units/mL

100 000 units/h

20 mL/h

100 mL NS over

units/kg/h

100 mL NS

30 min by IP

a, b See key, page 40. Abbreviations see key, page 40.