P1: PSB Printer: Yet To Come
9780521704632ind CUFX213A/Peck 9780521618168 December 29, 2007 17:19
362 Indexantibacterial drugs, 311 , 328t
activity,331t
aminoglycosides, 319 –320
fusidanes, 325 , 328t
glycopeptides, 322 –323
β-lactams, 311 –318
lincosamides, 323 –324
macrolides, 318 –319
nitroimidazoles,328t
prophylaxis guidelines,326t
quinolones, 320 –321
rifamycins, 324 –325
uses,329t
antibiotics
oral contraceptive failure, 21
see alsoantimicrobial agents
anticholinergics, 287 –289
effects,288t
anticholinesterases, 192 , 194f, 196
carbamylated enzyme complex formation,
193 –195
classification, 193 –196
easily reversible inhibition, 193
organophosphorus compounds,
195 –196
physiology, 175
anticoagulants
oral, 342 –344
during pregnancy, 16
anticonvulsants, 279 –281
antidepressants, 274 –278
atypical agents, 278
effects,275t
antidiuretic hormone (ADH), 259 –260
antiemetics, 282 –291
acupuncture, 291
anticholinergics, 287 –289
antihistamines, 289 –290
benzodiazepines, 291
dopamine antagonists, 283 –287
5-HT 3 antagonists, 290 –291
types, 282
antifibrinolytics, 345 –346
antifungal drugs,328t, 333
azoles, 332 –333
polyenes,328t, 332
antihistamines, 289 –290
antihypertensives, 258 –269
adrenergic neurone blockade, 263 –265
centrally acting drugs, 265 –268
drugs affecting renin–angiotensin–
aldosterone system, 258 –262
ganglion blockade, 268 –269
antimicrobial agents, 311 –334
antibacterial drugs, 311 , 328tantifungal drugs,328t, 333
antiviral drugs, 333 –334
antimuscarinics, 295
antiplatelet drugs, 337 –339
antithrombin III, 335 –336
antiviral drugs, 333 –334
anxiolytics, 270 –274
aprotinin, 345 –346
area under the curve (AUC),9f, 62–63, 71
β-arrestin, 28
aspirin, 38 , 153–154, 337
ionization, 6
kinetics, 154
mechanism of action, 153
metabolism, 153
overdose, 153 –154
treatment with sodium bicarbonate, 42
structure,152f
thromboembolism prevention, 149 –151
asthma, NSAID-sensitive, 151
asymptote, 52 –54
hyperbolic function, 54
atenolol,224t
atipamezole, 268
atracurium, 90 , 189
kinetics, 189
cis-atracurium, 18 , 189–190
atrioventricular nodal re-entrant tachycardia,
230f
atropine, 287 –289
blood–brain barrier crossing, 15
racemic, 48
autonomic nervous system, 197 , 198f
transmitters,199t
azithromycin, 318 –319
azlocillin, 314 –315
azoles, 332 –333
aztreonam, 318β-agonists, 207 –211
β 2 -agonists, inhaled, 13
barbiturates, 88 , 102–103
GABAAreceptors, 101 –102
intravenous use, 103 –108
keto-enol transformation,105f
lipid solubility,104t
protein binding,104t
barbituric acid,103f
β-blockersseeβ-adrenoceptor antagonists
bendrofluazide, 305 –307
benzamides, 286 –287
benzodiazepines, 89 , 270–274, 281
antiemetic use, 291
kinetics,272t
structure, 271 , 271f