ALCOHOLS FROM CARBONYL COMPOUNDS.
OXIDATION-REDUCTION AND
ORGANOMETALLIC COMPOUNDS
THE TWO ASPECTS OF THE COENZYME NADH
- The role of many of the vitamins in our diet is to become coenzymes for
enzymatic reactions.
- Coenzymes are molecules that are part of the organic machinery used by some
enzymes to catalyze reactions.
- The vitamins niacin (nicotinic acid, 菸鹼酸) and its amide niacin amide are
precursors to the coenzyme nicotinamide adenine dinucleotide.
Nicotine
N
N N
N
NH 2
Adenine
N
N CH^3
Niacin (Nicotinic acid)
N
OH
O
Nicotinamide
N
NH 2
O
O
O
OH OH
H H
H
CH 2
H
Adenine
O
O
OH OH
H H
H
CH 2
H
P
− P
O
O
O
−O
O
C NH
2
H O
N+
O
O
OH OH
H H
H
CH 2
H
Adenine
O
O
OH OH
H H
H
CH 2
H
P
− P
O
O
O
−O
O
C NH
2
H O
N
H
nicotinamide adenine dinucleotide reduced nicotinamide adenine dinucleotide
NAD+ NADH