Advices For Studying Organic Chemistry

(Wang) #1

ALCOHOLS FROM CARBONYL COMPOUNDS.


OXIDATION-REDUCTION AND


ORGANOMETALLIC COMPOUNDS


THE TWO ASPECTS OF THE COENZYME NADH



  1. The role of many of the vitamins in our diet is to become coenzymes for
    enzymatic reactions.



  1. Coenzymes are molecules that are part of the organic machinery used by some
    enzymes to catalyze reactions.



  1. The vitamins niacin (nicotinic acid, 菸鹼酸) and its amide niacin amide are
    precursors to the coenzyme nicotinamide adenine dinucleotide.


Nicotine

N
N N

N

NH 2

Adenine

N
N CH^3
Niacin (Nicotinic acid)

N

OH

O

Nicotinamide

N

NH 2

O

O
O

OH OH

H H
H

CH 2

H

Adenine

O
O

OH OH

H H
H

CH 2

H

P

− P
O

O

O
−O
O

C NH
2

H O

N+

O
O

OH OH

H H
H

CH 2

H

Adenine

O
O

OH OH

H H
H

CH 2

H

P

− P
O

O

O
−O
O

C NH
2

H O

N

H

nicotinamide adenine dinucleotide reduced nicotinamide adenine dinucleotide
NAD+ NADH

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