ECMO-/ECLS

Table 2: Definition of Organ dysfunction

Organ System

Definition of Organ Dysfunction

Cardiovascular
(dysfunction despite volume
expansion with ≥ 40 ml/kg of
isotonic fluids
in 1 hour)

Need for vasoactive

medications at any dose

(dopamine >5 mcg/kg/min)

OR: Presence of at least 2: Oliguria,
Lactic acidosis (>1 mmol/L),
Unexplained metabolic acidosis,
Capillary refill > 5 sec, Mottling, Core
to peripheral temperature gap >3°C
Respiratory (dysfunction
unrelated to congenital heart
disease or chronic lung disease

PaO 2 /FiO 2 <300 OR

PaCO 2 >65 OR

PaCO 2 20 mmHg >baseline

OR

FiO2 >50% for O2 saturation >92%
OR
Need for invasive or noninvasive
positive pressure ventilation
Neurologic GCS ≤ 11 or decrease by ≥ 3 from abnormal baseline
Hematologic Thrombocytopenia
(<100,00/mm^3 ) or decrease
by 50% over course of 3

OR Coagulopathy with INR > 2