0071483446.pdf

CHAPTER 13 Antimicrobials—Fighting Infection^221

Third Generation(continued)

Pregnancy Category: B

Route Dose Time

Cefpodoxime (Vantin, Proxetil)

Protein-Binding: 20%–40%

Half-Life: 2–3 hours

PO 200 mg Every 12 hours

Ceftazidime (Fortaz)

Protein-Binding: 10%–17%

Half-Life: 1–2 hours

IM /IV 0.5–2 g Every 8 to 12 hours

Ceftibuten (Cedax)

Protein-Binding: Unknown

Half-Life: 1.5–3 hours

PO 400 mg Once per day

Ceftriaxone (Recephin)

Protein-Binding: 85–95%

Half-Life: 8 hours

IV 1–2 g Every 24 hours

Ceftizoxime (Cefizox)

Protein-Binding: 30%–60%

Half-Life: 2 hours

IM/IV 500 mg Every 8 to 12 hours

Cefdinir (Omnicef)

Protein-Binding: Unknown

Half-Life: 1.7 hours

PO 300 mg or 600 mg/d Every 12 hours