1.2 Diverse Applications
Among the disciplines that use biophotonics tools and techniques are biomedical
research, clinical procedures, dentistry, drug development, healthcare, environ-
mental monitoring, food safety, and manufacturing process control, as Fig.1.4
illustrates [ 2 , 13 – 24 ].
- Biomedical research: Biophotonics tools and techniques are being used to
understand the basic functions of cells and molecules in life sciences, to dis-
cover the genesis of diseases in order to devise processes for their early
detection, to develop targeted therapies and minimally invasive treatments, and
to monitor health conditions for the prevention or control of diseases. - Clinical procedures: Almost every medical specialty makes use of some aspect
of biophotonics tools and techniques. Table1.3lists some examples from a
range of clinical procedures. In many of these disciplines the use of miniaturized
optical components together with fast photonics devices have made dramatic
improvements in response times and measurement accuracies. - Dentistry: The biophotonics concepts of laser-tissue interactions are having
widespread uses in dentistry for precisely focusing lasers at specific points in
hard dental enamel and bone without damaging the surrounding tissue to
remove infected tissue and to prepare teeth forfillings or crowns. Other laser
applications in dentistry include gum surgery, root canal sterilization, treatment
of oral cavity ulcers, and whitening of teeth. - Drug development: Processes such asflow cytometry,fluorescence detection
methods tofind out whether biological reactions are taking place in drug can-
didates, the use of photo-switchable inhibitory peptides that can be used to
manipulate protein-protein interactions inside cells by applying light, and sur-
face plasmon resonance techniques for rapidly assessing biological reactions in
Biomedical
research
Clinical
procedures
Biophotonics
tools and
techniques
POC tests
and analyses
Environmental
monitoring
Manufacturing
processes
controls
Drug
development
Food safety
Dentistry
Fig. 1.4 Applications of biophotonics tools and techniques
6 1 Overview of Biophotonics