Biophotonics_Concepts_to_Applications

(Dana P.) #1

1.2 Diverse Applications


Among the disciplines that use biophotonics tools and techniques are biomedical
research, clinical procedures, dentistry, drug development, healthcare, environ-
mental monitoring, food safety, and manufacturing process control, as Fig.1.4
illustrates [ 2 , 13 – 24 ].



  • Biomedical research: Biophotonics tools and techniques are being used to
    understand the basic functions of cells and molecules in life sciences, to dis-
    cover the genesis of diseases in order to devise processes for their early
    detection, to develop targeted therapies and minimally invasive treatments, and
    to monitor health conditions for the prevention or control of diseases.

  • Clinical procedures: Almost every medical specialty makes use of some aspect
    of biophotonics tools and techniques. Table1.3lists some examples from a
    range of clinical procedures. In many of these disciplines the use of miniaturized
    optical components together with fast photonics devices have made dramatic
    improvements in response times and measurement accuracies.

  • Dentistry: The biophotonics concepts of laser-tissue interactions are having
    widespread uses in dentistry for precisely focusing lasers at specific points in
    hard dental enamel and bone without damaging the surrounding tissue to
    remove infected tissue and to prepare teeth forfillings or crowns. Other laser
    applications in dentistry include gum surgery, root canal sterilization, treatment
    of oral cavity ulcers, and whitening of teeth.

  • Drug development: Processes such asflow cytometry,fluorescence detection
    methods tofind out whether biological reactions are taking place in drug can-
    didates, the use of photo-switchable inhibitory peptides that can be used to
    manipulate protein-protein interactions inside cells by applying light, and sur-
    face plasmon resonance techniques for rapidly assessing biological reactions in


Biomedical
research

Clinical
procedures

Biophotonics
tools and
techniques

POC tests
and analyses

Environmental
monitoring

Manufacturing
processes
controls

Drug
development

Food safety

Dentistry

Fig. 1.4 Applications of biophotonics tools and techniques


6 1 Overview of Biophotonics

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