197
Lo B, Parham L (2009) Ethical issues in stem cell research. Endocr Rev 30(3):204–213. http://
press.endocrine.org/doi/full/10.1210/er.2008-0031. Accessed 11 Jan 2015
Lovell-Badge R (2002) Stem cell therapy and research. Eur Rev 10:359–367. doi: 10.1017/
S1062798702000285
Ludwig TE, Levenstein ME, Jones JM, Berggren WT, Mitchen ER, Frane JL, Thomson JA (2006)
Derivation of human embryonic stem cells in defi ned conditions. Nat Biotechnol 24(2):185–
- doi: 10.1038/nbt1177
Medicine IO, Council NR (2002) Stem cells and the future of regenerative medicine. National
Academies Press, Washington, DC
Medicine IO, Council NR (2005) Guidelines for human embryonic stem cell research. National
Academies Press, Washington, DC
Mimeault M, Hauke R, Batra S (2007) Stem cells: a revolution in therapeutics—recent advances
in stem cell biology and their therapeutic applications in regenerative medicine and cancer
therapies. Clin Pharmacol Ther 82(3):252–264
Nakhaei-Rad S, Bahrami AR, Mirahmadi M, Matin MM (2012) New windows to enhance direct
reprogramming of somatic cells towards induced pluripotent stem cells. Biochem Cell Biol
90:115–123. doi: 10.1139/o11-064
Odorico JS, Kaufman DS, Thomson JA (2001) Multilineage differentiation from human embry-
onic stem cell lines. Stem Cells 19:193–204
Pearson H (2006) Brain can be made to self-repair. news@nature 1744-7933 http://dx.doi.
org/10.1038/news060619-14. Accessed 31 Oct 2014
Richards M, Fong CY, Chan WK, Wong PC, Bongso A (2002) Human feeders support prolonged
undifferentiated growth of human inner cell masses and embryonic stem cells. Nat Biotechnol
20:933–936
Rubin L (2008) Stem cells and drug discovery: the beginning of a new era? Cell 132(4):549–552
Sakata N, Sumi S, Yoshimatsu G, Goto M, Egawa S, Unno M (2012) Encapsulated islets transplan-
tation: past, present and future. World J Gastrointest Pathophysiol 3(1):19–26. doi: 10.4291/
wjgp.v3.i1.19
Schuldiner M, Yanuka O, Itskovitz-eldor J, Melton DA, Benvenisty N (2000) Effects of eight
growth factors on the differentiation of cells derived from human embryonic stem cells. Proc
Natl Acad Sci 97:11307
Solter D, Knowles BB (1975) Immunosurgery of mouse blastocyst. Proc Natl Acad Sci 72:5099
Tachibana M, Amato P, Sparman M, Gutierrez Nuria M, Tippner-Hedges R, Ma H, Kang E, Fulati
A, Lee HS, Sritanaudomchai H, Masterson K, Larson J, Eaton D, Sadler-Fredd K, Battaglia D,
Lee D, Wu D, Jensen J, Patton GS, Stouffer RL, Wolf D, Mitalipov S (2013) Human embryonic
stem cells derived by somatic cell nuclear transfer. Cell 153:1228–1238
Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and
adult fi broblast cultures by defi ned factors. Cell 126:663–676
Thomson JA, Itskovitz-eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM
(1998) Embryonic stem cell lines derived from human blastocysts. Science 282:1145–1147
Turetsky T, AIizenman E, Gil Y, Weinberg N, Shufaro Y, Revel A, Laufer N, Simon A, Abeliovich
D, Reubinoff BE (2008) Laser-assisted derivation of human embryonic stem cell lines from
IVF embryos after preimplantation genetic diagnosis. Hum Reprod 23:46–53
Tursken K (ed) (2012) Human embryonic stem cells handbook, New York London: New York
London : Humana Press.
Unger C, Skottman H, Blomberg P, Sirac Dilber M, Hovatta O (2008) Good manufacturing prac-
tice and clinical-grade human embryonic stem cell lines. Hum Mol Genet 17:R48–R53
Wert GD, Mummery C (2003) Human embryonic stem cells: research, ethics and policy. Hum
Reprod 18:672–682
Xu C, Inokuma MS, Denham J, Golds K, Kundu P, Gold JD, Carpenter MK (2001) Feeder-free
growth of undifferentiated human embryonic stem cells. Nat Biotechnol 19:971–974
Xu Y, Zhu X, Hahm HS, Wei W, Hao E, Hayek A, Ding S (2010) Revealing a core signaling regu-
latory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc
Natl Acad Sci 18:8129–8134. doi: 10.1073/pnas.1002024107
9 Human Embryonic Stem Cells and Associated Clinical Concerns