Novel Chemical Tools to Study Ion Channel Biology (Advances in Experimental Medicine and Biology)

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54 M. H. Akabas


Williams DB, Akabas MH (2002) Structural evidence that propofol stabilizes different GABA(A)
receptor states at potentiating and activating concentrations. J Neurosci 22(17):7417–7424.
doi:22/17/7417 [pii]
Wilson GG, Pascual JM, Brooijmans N, Murray D, Karlin A (2000) The intrinsic electrostatic po-
tential and the intermediate ring of charge in the acetylcholine receptor channel. J Gen Physiol
115(2):93–106
Winther JR, Thorpe C (2014) Quantification of thiols and disulfides. Biochim Biophys Acta
1840(2):838–846. doi:10.1016/j.bbagen.2013.03.031
Witter A, Tuppy H (1960) N-(4-Dimethylamino-3,5-dinitrophenyl)maleimide: a coloured sulf-
hydryl reagent. Isolation and investigation of cysteine-containing peptides from human and
bovine serum albumin. Biochim Biophys Acta 45:429–442
Wolf PA, Pollock ME (1964) Uptake of pentamethylene-1-5-C14-bis(methanethiosulfonate) in
comparison with the corresponding labeled bis(methanesulfonate). Antimicrob Agents Che-
mother 10:568–570
Wollmuth LP, Sobolevsky AI (2004) Structure and gating of the glutamate receptor ion channel.
Trends Neurosci 27(6):321–328. doi:10.1016/j.tins.2004.04.005
Wooltorton JR, McDonald BJ, Moss SJ, Smart TG (1997) Identification of a Zn2+ binding site on
the murine GABAA receptor complex: dependence on the second transmembrane domain of
beta subunits. J Physiol 505(3):633–640
Wu J, Kaback HR (1996) A general method for determining helix packing in membrane proteins
in situ: helices I and II are close to helix VII in the lactose permease of Escherichia coli. Proc
Natl Acad Sci U S A 93(25):14498–14502
Xu M, Akabas MH (1993) Amino acids lining the channel of the gamma-aminobutyric acid type A
receptor identified by cysteine substitution. J Biol Chem 268(29):21505–21508
Xu M, Akabas MH (1996) Identification of channel-lining residues in the M2 membrane-spanning
segment of the GABA(A) receptor alpha1 subunit. J Gen Physiol 107(2):195–205
Xu M, Covey DF, Akabas MH (1995) Interaction of picrotoxin with GABAA receptor channel-
lining residues probed in cysteine mutants. Biophys J 69(5):1858–1867
Yamagishi T, Janecki M, Marban E, Tomaselli GF (1997) Topology of the P segments in the so-
dium channel pore revealed by cysteine mutagenesis. Biophys J 73(1):195–204. doi:10.1016/
s0006-3495(97)78060-3
Yan RT, Maloney PC (1993) Identification of a residue in the translocation pathway of a membrane
carrier. Cell 75(1):37–44
Yu H, Kono M, Oprian DD (1999) State-dependent disulfide cross-linking in rhodopsin. Biochem-
istry 38(37):12028–12032. doi:bi990948+ [pii]
Zhang HG, ffrench-Constant RH, Jackson MB (1994) A unique amino acid of the Drosophila
GABA receptor with influence on drug sensitivity by two mechanisms. J Physiol 479(1):65–75
Zheng J, Zagotta WN (2000) Gating rearrangements in cyclic nucleotide-gated channels revealed
by patch-clamp fluorometry. Neuron 28(2):369–374

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