Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical, Part 1

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Table 17.1 Characterization of training programs used to evaluate the impact of exercise training
in pre-clinical models of Pulmonary Arterial Hypertension

References

Mode

of

exercise Intensity

Session

duration

(min)

Days

per

week

Total

duration

(weeks)

[ 35 ] AET FT 0.9 km/h 60 5 2

TP 40% Vmax 60 5 3

[ 34 ] AET^1 FT 15 cm/s 5 3 2

TP 50% Vmax, −15° slope 30 5 4

[ 33 ] AET FT 13.3 m/min 1 5 3

TP 13.3 m/min 30 5 4

[ 30 ] FT 6–15 m/min, 0–15° slope 5 5 5

HIIT TP 5x(2 min at 85–90% VO 2 R

and 3 min at 30% VO 2 R)

30 5 6

AET TP 50% VO 2 R 60 5 6

[ 26 ] AET FT 0.6 km/h–0.9 km/h 15–60 5 2

TP 60% VO2max 60 5 3

[ 32 ] AET FT 0.6 km/h–0.9 km/h 15–60 5 2

TP 60% VO2max 60 5 3

[ 25 ] AET FT 0.6 km/h–0.9 km/h 15–60 5 2

TP 60% VO2max 60 5 3

[ 28 ] FWR TP Free access to running

wheel

– 7 4

[ 31 ] AET FP Progressive increase from

0.6 km/h to 0.9 km/h

15–45 5 2

TP Progressive increase until

1.1 km/h by the 10th week;

0.8 km/h from 11th to 12th

week; 0.9 km/h in 13th

week

60 5 11

[ 86 ] AET FT NA NA 5 2

TP 0.6 km/h–0.9 km/h 50 5 5

[ 27 ] FT 20 m/min 20–60 5 1

AET TP-early 30 m/min 60 5 4

AET TP-late 30 m/min 60 5 2

[ 29 ] AET FT 20 m/min 20–60 5 1

TP 25 m/min 60 5 4

[ 81 ] AET TP 30 m/min, 10° slope 60 5 10

[ 24 ] AET TP 30 m/min, 10° slope 60 5 5

[ 85 ] AET TP 80% of Vmax 60 5 5

[ 84 ] AET TP 60% Vmax 30 5 3

FT familiarization to treadmill; TP training protocol; HIIT high intensity interval training; AET
continuous aerobic ExT; AET^1 downhill (negative slope) aerobic ExT; Vmax maximal running
speed; VO 2 R oxygen consumption reserve; NA information not available

17 Exercise Training in Pulmonary Hypertension and Right Heart Failure: Insights...