Multiphase Bioreactor Design

z dimensionless space coordinate in gel bead —

Subscripts

p product

s substrate

Superscripts
bulk bulk phase

int at the interface between two phases

n tank number in medium phase

o organic solvent phase

p gel bead phase

tox toxic

w medium phase

Greek
ηw viscosity medium phase Nm/s

∆ρ density difference Kg/m^3

ε 0 organic solvent phase hold-up —

εs gel bead phase hold-up —

εw medium phase hold-up —

ρ density Kg/m^3

σ interfacial tension N/m

pw mass transfer flux of product gel bead/water mol/s

mass transfer flux of product water/organic solvent mol/s

mass transfer flux of substrate water/gel bead mol/s

REFERENCES

Adlercreutz, P. (2000) Biocatalysis in non-conventional media, in Applied Biocatalysis, edited by
A.J.J.Straathof and P.Adlercreutz, 2nd edn., pp. 295–316. Singapore: Harwood Academic
Publishers.
Boeren, S., Laane, C. and Hilborst, R. (1992) The effect of alkanes on viability, enzyme induction
and enzyme activity in Flavobacterium dehydrogenans. In Biocatalysis in Non-conventional
media, edited by J.Tromper, M.H.Verrnuë, H.H.Beeftink, U.von Stockar, pp. 637–643.
Amsterdam: Elsevier Science Publ.

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