Biology 12

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Chapter 4 Homeostatic Mechanisms • MHR 133

CHAPTER 4 REVIEW


Summary of Expectations
Briefly explain each of the following points.


  • Homeostasis is the maintenance of the internal
    environment at a steady state, to ensure
    survival of a living organism; it is an example
    of dynamic equilibrium. (4.1)

  • The body’s reactions to increased or decreased
    temperature are examples of negative feedback
    loops, which are made up of three parts: a
    receptor, an integrator, and an effector. (4.1)

  • Negative feedback loops exist throughout the
    body to maintain homeostasis and prevent
    blood sugar, blood pressure, temperature, and
    other body constants from becoming too high
    or too low. (4.1)

  • Since homeostasis is essential to keeping the
    body healthy, negative feedback loops are
    common within the human body. (4.1)

  • The kidney’s principal function is to filter the
    blood to remove cellular waste products such
    as urea, creatinine, and uric acid from the
    body. (4.2)

  • The kidneys control water balance, pH, and
    the levels of sodium, potassium, bicarbonate,
    and calcium ions in the blood. (4.2)

  • Diabetes is a malfunction of the system that
    controls the levels of sugar (usually glucose)
    in the blood. (4.3)

  • The release of insulin — a hormone that
    lowers blood sugar levels — is controlled by
    the same type of negative feedback system that
    exists elsewhere in the body. In this case, the
    receptor, integrator, and effector are all found
    in each beta cell of the pancreas. (4.3)

  • Type 1 diabetes may be an autoimmune
    disease. (4.3)

  • The immune system activates a variety of
    white blood cells to attack foreign invaders
    such as bacteria and viruses. It recognizes and
    destroys damaged cells and irregular growths
    such as tumours. (4.4)

  • The immune system is primarily a function of
    two types of white blood cells — macrophages
    and lymphocytes. (4.4)

    • Cellular immunity is primarily a function of
      T cells. Antibody immunity is performed by
      B cells but initiated and controlled by T cells.
      (4.4)

    • An allergy is an inappropriate response by the
      body to a harmless material such as pollen,
      mould, or cat dander. (4.4)

    • Chemotherapy is the treatment of a disease
      using chemicals or drugs, but in today’s
      vocabulary its meaning has been limited to
      the treatment of cancers. (4.4)




Language of Biology
Write a sentence using each of the following words or
terms. Use any six terms in a concept map to show
your understanding of how they are related.


  • homeostasis • tubular secretion

  • interstital fluid • buffer

  • dynamic equilibrium • antagonistic hormones

  • vasoconstriction • insulin

  • hypothermia • glucagon

  • vasodilation • islets of Langerhans

  • hyperthermia • immunity

  • negative feedback loop • non-specific defence

  • sensory receptor • pathogen

  • integrator • phagocytosis

  • effector • macrophage

  • ureter • neutrophils

  • sphincter • monocyte

  • urethra • natural killer cell

  • cortex • specific immune

  • medulla system

  • pelvis • lymphocyte

  • nephron • cellular immunity

  • Bowman’s capsule • antibody immunity

  • proximal tubule • antigen

  • loop of Henle • helper T cell

  • distal tubule • cytotoxic T cell

  • collecting duct • suppressor T cell

  • glomerulus • memory T cell

  • nephric filtrate • apoptosis

  • re-absorption • histamines

  • isotonic • differentiation


1.Which homeostatic mechanisms help prevent
hyperthermia when you exercise on a hot day?


2.Why does homeostasis normally involve
negative feedback loops rather than positive
feedback loops?


3.Describe three homeostatic mechanisms that
help prevent dehydration of the body.
4.Why do people shiver in cold weather?

UNDERSTANDING CONCEPTS
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