452 Canine Sports Medicine and Rehabilitation
Flora, L., Hassing, G. S., Cloyd, G. G., Bevan, J. A.,
Parfitt, A. M. & Villanueva, A. R. 1981. The long‐
term skeletal effects of EHDP in dogs. Metab Bone
Dis Relat Res, 3, 289–300.
Fourie, S. L. & Kirberger, R. M. 1999. Relationship of
cervical spinal cord diameter to vertebral dimen
sions: a radiographic study of normal dogs. Vet
Radiol Ultrasound, 40, 137–143.
Frost, H. M. 1960. Presence of microscopic cracks in
vivo in bone. Henry Ford Hosp Med Bull, 8, 25–35.
Godde, T. & Steffen, F. 2007. Surgical treatment of
lumbosacral foraminal stenosis using a lateral
approach in twenty dogs with degenerative lum
bosacral stenosis. Vet Surg, 36, 705–713.
Griffiths, I. R. & Duncan, I. D. 1975. Chronic degen
erative radiculomyelopathy in the dog. J Small
Anim Pract, 16, 461–471.
Grillner, S. 1975. Locomotion in vertebrates: central
mechanisms and reflex interaction. Physiol Rev, 55,
247–304.
Handa, Y., Naito, A., Watanabe, S., Komatsu, S. &
Shimizu, Y. 1986. Functional recovery of locomo
tive behavior in the adult spinal dog. Tohoku J Exp
Med, 148, 373–384.
Hansen, H. J. 1951. A pathologic‐anatomical interpre
tation of disc degeneration in dogs. Acta Orthop
Scand, 20, 280–293.
Hasegawa, K., Turner, C. H., Chen, J. & Burr, D. B.
- Effect of disc lesion on microdamage accumu
lation in lumbar vertebrae under cyclic compres
sion loading. Clin Orthop Relat Res, 311, 190–198.
Ivansson, E. L., Megquier, K., Kozyrev, S. V., Muren,
E., Baranowska‐Korberg, I., Swofford, R., et al. - Variants within the SP110 nuclear body pro
tein modify risk of canine degenerative myelopa
thy. Proc Natl Acad Sci USA, 113, E3091–E3100.
Jaggy, A. 2010. Atlas and Textbook of Small Animal
Neurology. Hannover, Germany: Schlutersche, pp.
334–360.
Johnston, P. E., Knox, K., Gettinby, G. & Griffiths, I. R. - Serum alpha‐tocopherol concentrations in
German shepherd dogs with chronic degenerative
radiculomyelopathy. Vet Rec, 148, 403–407.
Jones, J. C. & Inzana, K. D. 2000. Subclinical CT
abnormalities in the lumbosacral spine of older
large‐breed dogs. Vet Radiol Ultrasound, 41, 19–26.
Kanazono, S., Pithua, P., Johnson, G. C., Gilliam, S. N.,
Johnson, G. S., O’brien, D. P. & Coates, J. R. 2013.
Clinical progression of canine degenerative mye
lopathy. American College of Veterinary Internal
Medicine Annual Forum. Seattle, WA June 16–18, - J Vet Int Med, 24(3), 699.
Kathmann, I., Cizinauskas, S., Doherr, M. G., Steffen,
F. & Jaggy, A. 2006. Daily controlled physiotherapy
increases survival time in dogs with suspected
degenerative myelopathy. J Vet Intern Med, 20,
927–932.
Kiehn, O. 2006. Locomotor circuits in the mammalian
spinal cord. Annu Rev Neurosci, 29, 279–306.
Kranenburg, H. C., Westerveld, L. A., Verlaan, J. J.,
Oner, F. C., Dhert, W. J., Voorhout, G., et al. 2010.
The dog as an animal model for DISH? Eur Spine J,
19, 1325–1329.
Kranenburg, H. C., Voorhout, G., Grinwis, G. C.,
Hazewinkel, H. A. & Meij, B. P. 2011. Diffuse idio
pathic skeletal hyperostosis (DISH) and spondylo
sis deformans in purebred dogs: a retrospective
radiographic study. Vet J, 190, e84–90.
Lee, T. C., Mohsin, S., Taylor, D., Parkesh, R.,
Gunnlaugsson, T., O’brien, F. J., et al. 2003.
Detecting microdamage in bone. J Anat, 203,
161–172.
Leep Hunderfund, A. N. & Wijdicks, E. F. 2009.
Intramedullary spinal cord hemorrhage (hemato
myelia). Rev Neurol Dis, 6, E54–E61.
Lornez, M., Coates, J. C. & Kent, M. 2010. Handbook of
Veterinary Neurology, 5th edn. St. Louis, MO:
Saunders, pp. 432–440.
March, P. A., Coates, J. R., Abyad, R. J., Williams, D.
A., O’brien, D. P., Olby, N. J., et al. 2009.
Degenerative myelopathy in 18 Pembroke Welsh
Corgi dogs. Vet Pathol, 46, 241–250.
Matthews, N. S. & de Lahunta, A. 1985. Degenerative
myelopathy in an adult miniature poodle. J Am Vet
Med Assoc, 186, 1213–1215.
Mayhew, P. D., Kapatkin, A. S., Wortman, J. A. & Vite,
C. H. 2002. Association of cauda equina compres
sion on magnetic resonance images and clinical
signs in dogs with degenerative lumbosacral ste
nosis. J Am Anim Hosp Assoc, 38, 555–562.
Morgan, B. R., Coates, J. R., Johnson, G. C., Bujnak, A.
C. & Katz, M. L. 2013. Characterization of intercos
tal muscle pathology in canine degenerative mye
lopathy: a disease model for amyotrophic lateral
sclerosis. J Neurosci Res, 91, 1639–1650.
Morgan, B. R., Coates, J. R., Johnson, G. C., Shelton,
G. D. & Katz, M. L. 2014. Characterization of tho
racic motor and sensory neurons and spinal nerve
roots in canine degenerative myelopathy, a poten
tial disease model of amyotrophic lateral sclerosis.
J Neurosci Res, 92, 531–541.
Motoie, H., Nakamura, T., O’uchi, N., Nishikawa, H.,
Kanoh, H., Abe, T. & Kawashima, H. 1995. Effects
of the bisphosphonate YM175 on bone mineral
density, strength, structure, and turnover in
ovariectomized beagles on concomitant dietary
calcium restriction. J Bone Miner Res, 10, 910–920.
Norrdin, R., Robinson, H., Powers, B. & Histand, B.- Evaluation of microdamage in canine
trabecular bone in hyperadrenocorticism and radi
ation injury. In: 22nd International Workshop on
Hard Tissue Biology, Sun Valley, Idaho.
Ogawa, M., Uchida, K., Yamato, O., Inaba, M., Uddin,
M. M. & Nakayama, H. 2014. Neuronal loss and