Devita, Hellman, and Rosenberg's Cancer

LWBK1006-09 LWW-Govindan-Review December 12, 2011 18:51

CHAPTER 9 PRINCIPLES OF

IMMUNOTHERAPY

SARA K. BUTLER•SAIAMA N. WAQAR

DIRECTIONS Each of the numbered items below is followed by lettered answers. Select the

ONE lettered answer that is BEST in each case unless instructed otherwise.

QUESTIONS

Question 9.1. Which of the following types of immunity is most responsible for the host

response to tumor development?

A. Humoral immunity

B. B-cell–mediated immunity

C. T-cell–mediated immunity

D. Antibody-mediated immunity

Question 9.2. Currently, what is the proposed mechanism for using immunotherapy to

destroy cancer cells?

A. Develop antibodies to target growth factors on cancer cells

B. Increase levels of immune lymphocytes

C. Develop antibodies to directly destroy the cancer cells

D. Increase levels of antigen-presenting cells

Question 9.3. Which of the following is NOT an approach to identify antigens involved

on tumor cells?

A. Developing antibodies to identified peptides and assessing presenta-

tion on the cancer cell surface

B. Developing tumor-reactive T cells to detect identified peptides on

cancer cell surface

C. Using T cells to assess cytokine release or lysis when present with

cancer cells

D. Using antisera from patients with cancer to screen cancer DNA

libraries

Corresponding Chapter inCancer: Principles & Practice of Oncology,Ninth Edition: 30 (Cancer Immunotherapy).

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