102
N (N2 or N3) stages but M is equal to M0. Stage IVB is
equivalent to previous stage IV in which distant metastases is
present (M1).
(B) Table 2 shows the difference between the staging in
esophageal adenocarcinoma with and without preopera-Table 2
Comparisons of the staging in esophageal adenocarcinoma in patients with and without preoperative
neoadjuvant therapy
Yp TNM (post neoadjuvant
therapy) p TNM (pathological)Stage T N M Stage T N M Grade0 Tis N0 M0 NA
I T0 N0 M0
T1 N0 M0 IA T1a N0 M0 G1/GX
IB T1a N0 M0 G2
T1b N0 M0 G1-2/GX
1C T1 N0 M0 G3
T2 N0 M0 T2 N0 M0 G1-2
IIA T2 N0 M0 G3/GX
II T3 N0 M0 IIB T3 N0 M0 Any
IIIA T0 N1 M0
T1 N1 M0 T1 N1 M0 Any
T2 N1 M0 IIIA T2 N1 M0 Any
IIIB T3 N1 M0
T1 N2 M0 T1 N2 M0 Any
T2 N2 M0 IIIB T2 N2 M0 Any
T3 N1 M0 Any
T4a N0 M0 T4a N0 M0 Any
T3 N2 M0 T3 N2 M0 Any
IVA T4a N1 M0 T4a N1 M0 Any
T4a N2 M0 IVA T4a N2 M0 Any
T4a NX M0
T4b AnyN M0 T4b AnyN M0 Any
AnyT N3 M0 AnyT N3 M0 Any
IVB AnyT AnyN M1 IVB AnyT AnyN M1 Any
GX grade cannot be determined, NX lymph node status cannot be determined
Alfred K. Lam