Marie Claire Australia — June 2017

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DRUG-FREE
MOOD BOOSTERS

OMEGA-3
Some studies report that
Omega-3 (found in oily fish)
improves mental wellbeing.

AROMATHERAPY
Balances and relaxes the nervous
system, easing tension and anxiety
and lowering blood pressure.

EXERCISE
Releases endorphins and
increases serotonin, regulating
mood, libido, appetite and sleep.

ST JOHN’S WORT
A herbal remedy that prevents
nerve cells in the brain from
reabsorbing serotonin.

YOGA
Paired with deep breathing, yoga
may alleviate mild depression by
reducing stress and anxiety.

HERE’S THE DEAL
The aforementioned study was inspired
by “facial feedback hypothesis”: our
facial expressions send signals to our
brain and influence our emotions. In
theory, if you can’t frown or show sad
expressions, you won’t feel as depressed.
Although researchers still don’t
know exactly how Botox functions as a
mood lifter, it doesn’t appear to work
along the same pathways as antide-
pressants. “We know people who have
failed every antidepressant [and]
respond very well to Botox,” says Dr
Eric Finzi, study co-author and assis-
tant professor of psychiatry at George
Washington University in the US.
Botox does not treat depression by
improving looks, he notes. “I have

patients who are 25 years old [with no
wrinkles] and I treat them with Botox
and their depression goes away.”
When administered correctly,
Botox is believed to be safe. Sydney
dermatologist Dr Naomi McCullum
says bruising is the most common
side effect. Longer-term repercussions
include brow asymmetry and ptosis
(drooping of the eyelids). Dr McCullum
also uses Botox to treat jaw-clenching
and sweating, while other doctors have
utilised it to combat migraines, spasms
and even urinary incontinence.

THE DOWNSIDE
Professor Mitchell isn’t convinced that
Botox is a cure-all, as there was poten-
tial for bias in Dr Finzi’s study.
Depressed participants were injected
with either Botox or saline. Six weeks
later participants were assessed, but
because three-quarters of the psychia-
trists could visibly tell who had been
injected with Botox, the results could
have been skewed.
“I’d be circumspect about putting
too much effort into saying this
[Botox] is something clinicians should
be using,” he says.
Botox is also a lot more expensive
than antidepressants. While the drug
can cost as little as $10 per month,
Botox is around $500 for 29 units, last-
ing three to four months.
After Botox, some of Dr Finzi’s
patients have been able to lower their
dosage of medication or stop taking
some meds under the care of a psychia-
trist. Botox may also help other disor-
ders, such as anxiety. “We think there’s
a good likelihood that we will have
significant improvement in some of our
patients,” says Dr Finzi. Stay tuned.

START A
CONVERSATION
Know someone affected by
depression? Join R U OK?’s
mission to inspire one million
conversations ahead of its
awareness day on September


  1. Find out more at
    ruok.org.au.


One in


5
women in

Australia will


experience
depression^

WELLNESS
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