Scientific American - USA (2020-03)

March 2020, ScientificAmerican.com 37 (In early October 2019, at yet another “tension” meeting, the dispute took a personal turn ...

38 Scientific American, March 2020 THE HIDDEN TOLL OF WILDFIRE AS BLAZES WORSEN GLOBALLY, AN AERIAL CAMPAIGN SEEKS TO UNDERSTAND ...

March 2020, ScientificAmerican.com 39 © 2020 Scientific American ...

40 Scientific American, March 2020 “This is inTeresTing. Not too thick,” said Jim Crawford, an atmospheric chemist wearing a mot ...

March 2020, ScientificAmerican.com 41 improve the accuracy of wildfire-emissions forecasts, so that coaches know better when to ...

42 Scientific American, March 2020 Forest conditions also play a significant role in worsening fires. After 100 years of aggress ...

March 2020, ScientificAmerican.com 43 the age of fire had arrived, millions of dollars in funding for major research campaigns f ...

44 Scientific American, March 2020 ples and stuck them into a Teflon sack lit by ultraviolet lights to simulate sunlight. They w ...

March 2020, ScientificAmerican.com 45 plants by flames is entrained in smoke and wafted into the upper troposphere by the fire’s ...

46 Scientific American, March 2020 Photographs by Ethan Hill Finally Making Sense A long-disdained therapy that targets RNA is a ...

March 2020, ScientificAmerican.com 47 © 2020 Scientific American ...

48 Scientific American, March 2020 A t her first birthday, emma Larson was not waLking or standing, but neither are plenty of ot ...

March 2020, ScientificAmerican.com 49 ease, but they found such serious prob- lems with toxicity and delivery that many abandone ...

50 Scientific American, March 2020 created a custom antisense drug for one little girl with an ultra- rare disease in less than ...

March 2020, ScientificAmerican.com 51 molecular properties that determine drug delivery and distribu- tion into tissues, and the ...

52 Scientific American, March 2020 “The closer you start the treatment relative to birth or disease onset, the more you can achi ...

March 2020, ScientificAmerican.com 53 Nusinersen, Antisense’s Dramatic Success Story Antisense oligonucleotides, or ASOs, are sh ...

54 Scientific American, March 2020 AUTHORS at their laboratory for researching prion disease at the Broad Institute in Cambridge ...

Photographs by Ethan Hill March 2020, ScientificAmerican.com 55 Treating susceptible individuals while they are still healthy of ...

56 Scientific American, March 2020 N o one expects to live a before-and-after kind of life, divided into the moments before and ...