Nature - USA (2020-01-16)

temperature followed by secondary antibody (donkey anti-rabbit 488, 1:1,000; donkey anti-goat 555, 1:1,000) diluted in 1 × PBS/5 ...

Article CGRP-θ cells, 37 CGRP-ζ cells, 555 MRGPRD cells, 37 proprioceptors, 24 SST cells, 105 cold thermoceptor cells; Extended ...

Li, C. L. et al. Somatosensory neuron types identified by high-coverage single-cell RNA- sequencing and functional heterogeneit ...

Article Extended Data Fig. 1 | Quality control metrics for DRG sensory neuron scRNA-seq data and canonical correlation analysis. ...

Extended Data Fig. 2 | Somatosensory neuron subtype composition varies across axial levels. a, Left, schematic representing whic ...

Article Extended Data Fig. 3 | Dorsal root ganglia and trigeminal ganglia comprise similar subtypes of somatosensory neurons. a, ...

Extended Data Fig. 4 | Neural crest progenitors, sensory neuron progenitors and unspecialized sensory neurons express highly dis ...

Article Extended Data Fig. 5 | Force-directed layout of putative subtype-restricted transcription factors. a, Force-directed lay ...

Extended Data Fig. 6 | Expression of somatosensory neuron subtype- specific genes during development. a, Box plots representing ...

Article Extended Data Fig. 7 | DRG counts and TF analysis in Pou4f 2 and Pou4f3 mutants. a, Representative images of Avil smRNA- ...

Extended Data Fig. 8 | See next page for caption. ...

Article Extended Data Fig. 8 | Generation and validation of Bmpr1bT2a-Cre and Avpr1aT2a-Cre mouse lines. a, Targeting strategy f ...

Extended Data Fig. 9 | Subtype-restricted TF expression prof iles in Ng f−/− Bax−/− cell clusters. a, Heat map depicting express ...

1 nature research | reporting summary October 2018 Corresponding author(s): David Ginty Last updated by author(s):Oct 17, 2019 R ...

2 nature research | reporting summary October 2018 Field-specific reporting Please select the one below that is the best fit for ...

3 nature research | reporting summary October 2018 Mycoplasma contamination Cell lines were not tested for myco contamination Co ...

Nature | Vol 577 | 16 January 2020 | 399 Article Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s dis ...

400 | Nature | Vol 577 | 16 January 2020 Article Data Fig. 2). We then used spanning-tree progression analysis of den- sity-norm ...

Nature | Vol 577 | 16 January 2020 | 401 surrounding blood vessels in control brains (Extended Data Fig. 7a). Notably, we detect ...

402 | Nature | Vol 577 | 16 January 2020 Article cytotoxic proinflammatory CD8+ TEMRA cells in the CSF of patients with age-rela ...