Science 14Feb2020

aggregates;Flrepresents a subset ofbbl,which additionally includes fecal and detrital matter ( 21 ). Between May 2013 and Februa ...

using the same parameterizations ( 24 ), large- particle (bbl) specific fragmentation rates were notably higher in the Southern ...

PHYSICS Twisted bulk-boundary correspondence of fragile topology Zhi-Da Song^1 , Luis Elcoro^2 , B. Andrei Bernevig1,3,4* A topo ...

an EBR at the empty Wyckoff position, where no atom exists, it forms an obstructed atom- ic insulator band. The model, in the ba ...

(449A⊕ 449 B⊕ 449 ð^1 EÞ⊕ 449 ð^2 EÞ), remain un- changed. We generalize theC 4 symmetric TBC: hm;ajH^ðlÞjn;bi¼ hm;ajH^ð 1 Þjn;b ...

state. One can verify that the band structure shown in Fig. 2B satisfies this inequality and hence has a fragile topology. [See ...

PHYSICS Experimental characterization of fragile topology in an acoustic metamaterial Valerio Peri^1 , Zhi-Da Song^2 , Marc Serr ...

spectral information shown in Fig. 2A. Evalu- ating the relative weight and phase at different Wyckoff positions inside the unit ...

d=m(B)–m(A) (3) which counts the imbalance betweenC 2 -odd andC 2 -even states (Fig. 2B). One can now smoothly disconnect the sa ...

Engineering Center DMR-142051, the Packard Foundation, and the Schmidt Fund for Innovative Research. B.A.B. is also supported by ...

CIRCADIAN RHYTHMS Circadian rhythms in the absence of the clock geneBmal1 Sandipan Ray1,2, Utham K. Valekunja1,2, Alessandra Sta ...

temperatures ( 1 ). To determine whether transcriptomic oscillations seen in the ab- sence ofBmal1exhibit this key characteristi ...

transcription factors) substitutes for BMAL1 function inBmal1−/−tissue or cells. What might, therefore, be the underlying molecu ...

expression of multiple ETS transcription fac- tors with comparable peak phases clustered arounddawn(Fig.3B).Bycontrast,wedid not ...

of the CLOCK-BMAL1-CRY1 complex has a strong inhibitory effect on the activity of other transcription factors, including ETS ( 2 ...

( 30 – 32 ), but not inBmal1−/−tissues. After syn- chronization with DEX, as described above, samples were harvested over two ci ...

STRUCTURAL BIOLOGY Structural basis of second-generation HIV integrase inhibitor action and viral resistance Nicola J. Cook^1 , ...

drugs displace the 3′viral DNA nucleotide, which stacks against the central body of the INSTI (fig. S14). In agreement with low- ...

empirical interpretation of the INSTI resist- ance mechanism. Our simulations show that analog 1 is con- siderablymoredynamicint ...

bond with Nd1 of conserved residue His^114 , prompting it to donate its Ne2protontoSer^140 (Fig. 2E and fig. S20). This extended ...