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256 | Nature | Vol 579 | 12 March 2020 Article Recurrent interactions in local cortical circuits Simon Peron1,4 ✉, Ravi Pancholi ...
Nature | Vol 579 | 12 March 2020 | 257 Subnetworks with increased connectivity (for example, 0.4) exhib- ited stronger amplifica ...
258 | Nature | Vol 579 | 12 March 2020 Article 961 ± 464 to 904 ± 384). Touch ablations produced significantly differ- ent chang ...
Nature | Vol 579 | 12 March 2020 | 259 neuron mean response. Response similarity was measured for each neuron as the correlation ...
Article Methods Network model We modelled the L2/3 network associated with a single barrel column— one of the most extensively s ...
30 randomized network instances for each subnetwork connectiv- ity level, number of ablations, and input rise time, and calculat ...
Article GaAsP PMTs (Hamamatsu). The 940 or 1,000 nm (Coherent) imaging beam was steered with a 16 kHz line rate resonant galvano ...
In virally transfected mice, the mCherry signal was used to restrict ablations to pyramidal neurons^7 ; in mice endogenously exp ...
Article Brette, R. et al. Simulation of networks of spiking neurons: a review of tools and strategies. J. Comput. Neurosci. 23 ...
Extended Data Fig. 1 | Effect of ablation in a simulated network with hyper- connectivity (that is, Pconn > 0.4; here, Pconn ...
Article Extended Data Fig. 2 | Multi-photon ablation protocol. a, Example field of view immediately before (left) and after (rig ...
Extended Data Fig. 3 | Multi-photon ablation produces spatially localized effects. a, Change in calcium event rate (Methods) as ...
Article Extended Data Fig. 4 | Effect of ablation on L2/3 model sensory representation increases with the number of ablated neur ...
Extended Data Fig. 5 | Ablation of touch neurons does not produce distance- dependent effects in the whisking representation. Pr ...
Article Extended Data Fig. 6 | Behaviour does not account for ablation effects. a, Pre-touch (dark blue) and post-touch (light b ...
Extended Data Fig. 7 | Example effects of ablations of whisking and silent neurons. a, Example ablation of a whisking neuron. Le ...
Article Extended Data Fig. 8 | Simulation of ablation of whisking neurons produces representation degradation in networks with i ...
Extended Data Table 1 | Individual mice are listed with the number of neurons imaged, the type(s) of ablation(s) performed, and ...
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