Science - USA (2019-02-15)

IMMUNOLOGY BCR-dependent lineage plasticity in mature B cells Robin Graf^1 †, Jane Seagal^2 ‡, Kevin L. Otipoby^2 *§, Kong-Peng ...

the expression of CD19, CD43, and CD5 (Fig. 2, D and E, and fig. S5B). In the case of the B1a- specific marker CD5, the up-regul ...

Grafet al.,Science 363 , 748–753 (2019) 15 February 2019 3of6 A Day 8 Day 30 Day 4 B2→B1 Spleen 3-8 6-8 5C5+ B2→B1 Ac146+ B2 IgM ...

in the absence of stimulation and faster dif- ferentiation into CD138+plasma cells upon lipo- polysaccharide (LPS) stimulation ( ...

result was further confirmed by a transcriptome- wide analysis, where the Spearman correlations between B2→B1 and B1 control sam ...

to colleagues whose work we could not cite because of space restrictions.Funding:Supported by NIH grant AI054636 and the Europea ...

STRUCTURAL BIOLOGY Structural insight into substrate and inhibitor discrimination by human P-glycoprotein Amer Alam^1 , Julia Ko ...

We observed two main conformations in our single-particle cryo-EM analysis (fig. S1). The highest-resolution structure (Fig. 1B) ...

and stacking interactions with aromatic side chains, as observed for other cholesterol-protein inter- actions ( 26 ). At the lev ...

more completely, and form a larger number of contacts with ABCB1. This suggests that, in a continuum of substrates and inhibitor ...

Apply for our exciting research Prize! The Science & PINS Prize is awarded for innovative research that modulates neural act ...

Download the meeting app for the most up-to-date program information:aaas.org/app AAAS, publisher ofScience, thanks the sponsors ...

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782 15 FEBRUARY 2019 • VOL 363 ISSUE 6428 sciencemag.org/custom-publishing SCIENCE new products: cell/tissue culture LIFE SCIENC ...

Science Immunologypublishes original, peer-reviewed, science-based research articles that report critical advances in all areas ...

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Director, Public Health Research Institute Rutgers New Jersey Medical School (NJMS) invites applicants for the position of Direc ...

The 2019 (35th) International Prize for Biology This year’s research field:Biology of Insects Please access at:http://www.jsps.g ...

I can’t access these funds until after the conference, long after paying for registration and flights. So, for the past 3 months ...