Science - USA (2020-08-21)

M. Ghidiu, M. W. Barsoum,J. Am. Ceram. Soc. 100 , 5395– 5399 (2017). Z. H. Fuet al.,Phys. Rev. B 94 , 104103 (2016). M. Jansen, ...

IMMUNOLOGY SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation Xin Wu^1 , Yun Wang^ ...

ofSostdc1EGFP/Bcl6RFPdual-reporter mice dem- onstrated that SOSTDC1+TFHcells (~5%) coexisted distinctly from SOSTDC1–TFHcells (~ ...

for antibody production, partially because of lower levels ofIl4andIl21,aswellassurface Cd154(CD40L) (Fig. 2, C to E, and fig. S ...

TFR,butnotCXCR5–Treg, cells were positively correlated with that inb-catenin–stabilized Tregcells ( 21 ) (Fig. 4C and fig. S12, ...

N. Macías-Seguraet al.,PLOS ONE 13 , e0194205 (2018). N. Haradaet al.,EMBO J. 18 , 5931–5942 (1999). T. Reyaet al.,Immunity 13 ...

NEUROSCIENCE Julich-Brain: A 3D probabilistic atlas of the human brain’s cytoarchitecture Katrin Amunts1,2†, Hartmut Mohlberg^1 ...

datasets, in combination with the complex- ityanddiversityoftheoverallreconstruction workflow, required time- and resource-effec ...

intersubject differences in volume (fig. S5), but differences between the two hemispheres were not significant at a global level ...

The areas and nuclei were also transformed to the stereotaxic MNI-Colin27 and ICBM2009casym reference space, using the computed ...

mapped and adjacent areas results in a thresh- old value of about 35%. Under the assumption that this threshold also applies to ...

DRUG DEVELOPMENT Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic Emily N. Chin^1 , Chenguang Yu1, ...

responsible for the clinical failure of 5,6- dimethylxanthone-4-acetic acid (DMXAA), a vascular disrupting agent that can functi ...

of a“pair of wings,”with an approximate antiparallel four-helix bundle making up an extensive buried dimer interface ( 19 , 20 ) ...

monomers are positioned to form hydrogen- bond interactions with both the carboxylic acid of one bound molecule of SR-717 and th ...

backbone phosphate of bound cGAMP (Fig. 2F). This facilitates formation of direct hydrogen-bond contacts with the guanidi- nium ...

Chinet al.,Science 369 , 993–999 (2020) 21 August 2020 6of7 Fig. 4. Impact of systemic SR-717 administration on antitumor immuni ...

NK cells revealed significantly reduced IFN-g+ NK cells in TILs (fig. S16C), with a modest but significant increase of IFN-g+NK ...

GLOBAL CARBON CYCLE Abrupt CO 2 release to the atmosphere under glacial and early interglacial climate conditions C. Nehrbass-Ah ...

glacial period (MIS 3) ( 28 ). Our results dem- onstrate that this correlation also applies to MIS 10a to 11a, thereby emphasizi ...