Medical Microbiology

136 2 BasicPrinciplesofImmunology

Table2. 13 Continued:ImportantCDAntigens

Designation

(alternatives)

Cellswhichexpressthe

antigen

Functions

CD2 1 (CR2) MatureBcells,follicular

dendriticcells

Receptorforthecomplement

components(CR)C3dandthe

Epstein-Barrvirus.Formsa

co-receptorforBcellstogether

withCD1 9 andCD8 1

CD22 MatureBcells AdhesionofBcellstomonocytes

andTcells

CD23(FceRII) MatureBcells,activated

macrophages,eosinophils,

folliculardendriticcells,

bloodplatelets

Low-affinityreceptorforIgE,and

ligandfortheCD19:CD21:CD8 1

coreceptor

CD25(Tac) ActivatedTcells,Bcells,

andmonocytes

achainoftheIL-2receptor,

associatedwithCD1 22 andthe

IL-2Rcchain

CD26 ActivatedBandTcells,

macrophages

Aproteasewhichmaybe

involvedinHIVentryintohost

cells

CD28 SubgroupofTcells,activated

Bcells

Activationofnaı ̈veTcells.

Areceptorforcostimulatory

signal(signal2);bindsCD80

(B7.1)andB7.2

CD29 Leukocytes b 1 subunitofc 1 integrins,asso-

ciatedwithCD49ainVLA-1

integrin

CD34 Hematopoieticprecursorcells,

capillaryendothelium

LigandforCD62L(L-selectin)

CD35(CR1) Erythrocytes,Bcells,mono-

cytes,neutrophilsandeosino-

phils,folliculardendriticcells

Complementreceptor1;binds

C3bandC4b.Alsomediates

phagocytosis

CD38 EarlyBandTcells,activated

Tcells,germinalcenterBcells,

plasmacells

B-cellproliferation?

CD39 ActivatedBcells,activated

naturalkillercells,macro-

phages,dendriticcells

Unknownfuction,butmay

mediateadhesionofBcells

2

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Kayser, Medical Microbiology © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.