Science - USA (2021-12-17)

Research Funding Available Up to $1M per lab Proposals due March 1, 2022 Ionis is funding investigators with extraordinarily ori ...

serve as a proxy for estimates of Omicron VOC prevalence ( 5 ) and help us to under- stand the fraction of infections caused by ...

norms to support better global responses to newly emerging variants. Lesley Scott^1 , Nei-yuan Hsiao2,3, Sikhuline Moyo^4 , Lava ...

Editor’s Note We thank J. G. Hering and colleagues for raising important questions about gender bias in cases of alleged bullyin ...

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1458 17 DECEMBER 2021 • VOL 374 ISSUE 6574 science.org SCIENCE al. used an approach com- monly used to predict spatially explici ...

SCIENCE science.org 17 DECEMBER 2021 • VOL 374 ISSUE 6574 1459 the pituitary-gonadal feed- back loop, which suppresses pituitary ...

1460 17 DECEMBER 2021 • VOL 374 ISSUE 6574 science.org SCIENCE RESEARCH | IN OTHER JOURNALS Halorhodospira, which is found in th ...

SCIENCE science.org 17 DECEMBER 2021 • VOL 374 ISSUE 6574 1460-B RESEARCH SPIN CHEMISTRY Quantum oscillations in radical pairs T ...

1460-C 17 DECEMBER 2021 • VOL 374 ISSUE 6574 science.org SCIENCE RESEARCH | IN SCIENCE JOURNALS excitation, cell division, metab ...

RESEARCH ARTICLE SUMMARY ◥ GENOMICS Pangenomics enables genotyping of known structural variants in 5202 diverse genomes Jouni Si ...

RESEARCH ARTICLE ◥ GENOMICS Pangenomics enables genotyping of known structural variants in 5202 diverse genomes Jouni Sirén^1 †, ...

These heuristics are configurable, and we present two presets: default Giraffe (written as just“Giraffe”) balances speed and acc ...

where no haplotype variation is known. To overcome these issues, Giraffe includes mech- anisms for creating synthetic haplotype ...

It was also faster at aligning to human graphs than Bowtie2 or BWA-MEM were at aligning to the corresponding linear reference. F ...

theGenomeinaBottle(GIAB)v4.2.1HG002 high-confidence variant-calling benchmark ( 24 ). Out of the examined pipelines, Giraffe map ...

complex, meaning that they are not directed, not acyclic, or not free of internal source and sink nodes. Mapping accuracy result ...

Fine-tuning SVs with frequencies SVs in the input catalogs may contain errors. When multiple alleles co-occur at an SV site, we ...

replicated these observations in the high- coverage 1000 Genomes Project dataset ( 31 ). Here, again, the PCA of the allele coun ...

an SV-eQTL, adjustedp= 0.008). As expected, SV-eQTLs were strongly enriched in coding, intronic, promoter, untranslated, and reg ...