Physics and Radiobiology of Nuclear Medicine

calculation of normalization factors and their storage are carried out by the manufacturer’s menu-driven software. Questions De ...

phy and Autoradiography: Principles and Applications for the Brain and Heart. New York: Raven; 1986:237–286. Keim P. An overview ...

14 Internal Radiation Dosimetry 208 Radiation can cause detrimental effects on human tissues, and these effects depend on variou ...

Another radiation unit is kerma(acronym for kinetic energy released in matter) which is defined as the sum of initial kinetic en ...

rem =rad ×Wr (14.7) The International Commission on Radiological Protection (ICRP) has sug- gested the Wrvalues for different ra ...

Dose Calculation The radiation absorbed dose depends on a number of factors: (1) the amount of radioactivity administered; (2) t ...

Here fi(v←r) is called the absorbed fractionand is defined as the ratio of the energy absorbed by the target volume vfrom the it ...

(14.13) Here,Teis the effective half-life of the radiopharmaceutical in hours (dis- cussed in Chapter 3). If t=∞, that is, the r ...

There are situations when the uptake of the tracer is gradual and the clearance also is slow. In these cases, =1.44f·AoTe(TQ/TU) ...

Dose Calculation 215 T able 14.3. S*, mean absorbed dose per unit cumulated activity (rad/ mCi · hr) †for 99m Tc. Source organs ...

Answer The half-life of 99mTc =6 hr. The effective half-life of two biological clear- ances are Using Eq. (14.17) =1.44 × 4000 × ...

Dose Calculation 217 The quantity 0.576NiEiis a constant and can be denoted by Dias in Eq. (14.10). Thus Di=0.576NiEi (14.24) Wi ...

218 14. Internal Radiation Dosimetry Table14.4.Continued Dose Radiopharmaceuticals Organ rad/mCi mGy/GBq 99mTc-mercaptoacetylgly ...

Dose Calculation 219 Table14.4.Continued Dose Radiopharmaceuticals Organ rad/mCi mGy/GBq (^131) I-iodide Thyroid 1300.00 3.5 × 1 ...

Effective Dose Equivalent and Effective Dose Historically, the whole-body dose or total body dose was used to evaluate the relat ...

the same probability of cancer induction in that organ. For example, a dose of 3 rem to the whole body causes some probability o ...

(ICRP 26) and ED (ICRP 60). Some WTvalues are different and some are the same in the two schema, whereas others are not given in ...

Questions 223 Table14.7. Fraction of adult administered dosages for pediatric administration. Weight in kg (lb) Fraction Weight ...

(c) Composition of the target organ (d) Amount of the radioactivity present in the source (e) Shape of the source organ Does th ...

Snyder WS, et al.“S” absorbed dose per unit cumulated activity for selected radio- nuclides and organs. MIRD pamphlet no. 11. Ne ...