Textbook of Personalized Medicine - Second Edition [2015]

305 chemotherapy after surgery by identifying them as having little risk of a relapse (Ellis et al. 2008 ). About 83 % of patien ...

306 indicator that a sample contains insuffi cient tumor cells to make a molecular diagnosis and that a new sample needs to be t ...

307 chemotherapy in some breast cancer patients, scientists at Dana-Farber Cancer Institute (Boston, MA) scanned the genome of s ...

308 Prediction of Adverse Reaction to Radiotherapy in Breast Cancer Radiotherapy is a very important treatment for breast cancer ...

309 a panel of 21 genes using RT-PCR. The likelihood of distant recurrence in patients with ER-positive breast cancer without in ...

310 in Danish patients who were treated with chemotherapy after removal of breast cancer tumors. That study used data from tumor ...

311 Prognostic Gene Biomarkers of Breast Cancer Three genes, homeobox 13 (HOXB13), interleukin-17B receptor (IL17BR) and CHDH, a ...

312 developed 14-gene metastasis score that predicts distant metastasis in breast cancer research subjects without systemic trea ...

313 to enter the blood stream to begin their deadly journey. The number of these “win- dows” correlated to the probability of di ...

314 the Curie Institute; Vall d’Hebron Institute of Technology; and Lund University. The partners plan to harmonize their method ...

315 Tamoxin Therapy for ER-Positive Breast Cancer For women with ER-positive early breast cancer, treatment with tamoxifen for 5 ...

316 (7 of 14) was the TP53 tumor suppressor, and aberrations were observed in additional tumor suppressor genes including CTNNA1 ...

317 occurred at >10 % incidence across all breast cancers; however, there were numerous subtype-associated and novel gene mut ...

318 pathway revealed that what are believed to be protein and phosphoproteomic signatures of PI3K activation did not correlate w ...

319 Early Diagnosis of Ovarian Cancer Two tumor biomarkers, CA125 and one approved by FDA called HE4, are used to track whether ...

320 hypothesis that these tumors have continued dependence on such 3′UTR lesions, and that direct targeting may be a viable futu ...

321 Recurrent and Drug-Resistant Ovarian Cancer To identify the best treatment for recurrent ovarian cancer, researchers at Yale ...

322 or downregulation of the lipid transporter LRP1B emerged as a signifi cant correlate of acquired resistance in the analysis. ...

323 Interruption of multiple specifi c biochemical pathways may be a promising therapeutic strategy in ovarian carcinomas that e ...

324 (The Cancer Genome Atlas Research Network 2011 ). The equipment used included Agilent, Illumina, and Affymetrix arrays to lo ...