Textbook of Personalized Medicine - Second Edition [2015]

650 Personalized Medicine in Israel The Israel National Center for Personalized Medicine (INCPM), located at the Weizmann Instit ...

651 genetically predisposing risks without having to change their lifestyle. Rather than worrying about such theoretical concern ...

652 Limitations of Personalized Medicine Limitations of personalized medicine are shown in Table 20.8. One of the limitations of ...

653 account for most patient morbidity and mortality is the most futuristic and technically the most complicated, element of the ...

654 References Adida B, Kohane IS. GenePING: secure, scalable management of personal genomic data. BMC Genomics. 2006;7:93. Blum ...

K.K. Jain, Textbook of Personalized Medicine, DOI 10.1007/978-1-4939-2553-7_21, 655 © Springer Science+Business Media New York 2 ...

656 the populations in which they are to be used and the delivery of pharmacogenetic testing should be made as straightforward a ...

657 cover information about data security and about the governance structure and the mechanism for considering research protocol ...

658 A commentary in the Journal of American Medical Association offers several caveats and recommendations to help doctors and c ...

659 result in large databases of genomic information. The magnitude of the genomic scans, implications of the inclusion of genet ...

660 Genetic information about the patient, confi ded only to the physician in tradi- tional medicine, will be accessible to oth ...

661 vasodilators is more effective in treating heart failure in black persons than in white persons and that ACE inhibitors have ...

662 ApoEε4 confers a risk of Alzheimer’s disease in a population-specifi c manner. As compared with the risk among those who do ...

663 Genomic information is now increasingly replacing self-reported race in medical- and population-related research. With the a ...

664 covering BRCA1 and BRCA2; mutations in these genes are linked to an increased risk for breast and ovarian cancer. Both sides ...

K.K. Jain, Textbook of Personalized Medicine, DOI 10.1007/978-1-4939-2553-7_22, 665 © Springer Science+Business Media New York 2 ...

666 FDA and Personalized Medicine Consistent with its core mission, the FDA’s is working in collaboration with research- ers, dr ...

667 FDA and Pharmacogenomics Pharmacogenomics is an area of development the FDA views very positively. The FDA has received nume ...

668 The FDA believes that pharmacogenomic testing can be smoothly integrated into drug development processes. Currently, scienti ...

669 at the top of the label. With a pharmacogenomics section in new labels, FDA is plan- ning ahead to reserve a spot in the lab ...