Science - USA (2022-01-07)
outcomes of similar value according to their identity (milk or sucrose). This distinction was encoded by distinct neuronal activ ...
from the floor. Lever extensions and retrac- tions and nose poke port opening and clos- ing (guillotine door) were remotely cont ...
Fig. 4 and figs. S10 and S11), sessions were structured as follows: (i) 5 min without action or outcome availability (OFF task); ...
with the nVista2 system) and 1280 × 800 pixels (~768 × 480mm, nVista3 system). Imaging frame time stamps were recorded with the ...
the laser was switched on from the first lick after outcome delivery until the last rewarded lick of each consumption period. Li ...
To address the unbalanced design (more non- task-related epochs) we used theFscore cal- culated from the confusion matrices as a ...
C. Herryet al., Switching on and off fear by distinct neuronal circuits.Nature 454 , 600–606 (2008). doi:10.1038/ nature07166; ...
GOLDOPENACCESS,DIGITAL,ANDFREETO ALLREADERS AsAAAS’s firstmultidisciplinary, openaccessjournal,ScienceAdvancespublishes research ...
RESEARCH ARTICLES ◥ CORONAVIRUS Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial Peter B. Gi ...
COVE follows participants for 2 years, which will enable future analyses of how the current level of antibodies correlates with ...
The estimated cumulative incidence of COVID- 19 by the end of blinded follow-up (100 days after day 57) for the entire vaccine g ...
titer, which suggests a smooth incremental change in risk with titer (Fig. 4A). Based on the Coxmodel,Fig.4Bshowsestimatedcumula ...
(supplementary text, section S2) supported the inference that vaccine efficacy was generally higher for the upper versus lower t ...
over time in relation to the timing of break- through infections of variants with variable neutralization sensitivity, with the ...
vaccine efficacy add evidence toward estab- lishing an immune marker surrogate end point for mRNA COVID-19 vaccines. Moreover, t ...
R. A. Koupet al.,Nat. Med. 27 , 1493–1494 (2021). J. Kerteset al.,medRxiv2021.09.01.21262957 [Preprint] (2021). https://doi.org ...
SF3B6 (p14), which has no homolog inSac- charomyces cerevisiae, was shown to cross-link to the BP-A in HeLa nuclear extract, ind ...
the BP-A. Similar minimal substrates have been used previously ( 27 , 28 ). We immobilized 17SU2 snRNP on anti-GFP nanobody resi ...
incompatible with those later splicing com- plexes, indicating that the A-like U2 snRNP represents a distinct splicing intermedi ...
the DDX46 helix are missing from these two reconstructions, consistent with the biochem- ical data and the sample preparation pr ...
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