Science - USA (2022-01-21)
665 – 680 (2020). doi:10.1038/s41592-020-0848-2; pmid: 32483333 B. Coventry, D. Baker, Protein sequence optimization with a pai ...
RESEARCH ARTICLE SUMMARY ◥ SYNTHETIC BIOLOGY Synthetic multistability in mammalian cells Ronghui Zhu, Jesus M. del Rio-Salgado, ...
RESEARCH ARTICLE ◥ SYNTHETIC BIOLOGY Synthetic multistability in mammalian cells Ronghui Zhu^1 , Jesus M. del Rio-Salgado^1 , Jo ...
Zhuet al.,Science 375 , eabg9765 (2022) 21 January 2022 2 of 11 A Ideal capabilities for a synthetic multistable circuit B Natur ...
Zhuet al.,Science 375 , eabg9765 (2022) 21 January 2022 3 of 11 mCitrine- mCitrine+ WT R39A R2AR39AR2AR39AR67A Mutations 1 10 20 ...
Zhuet al.,Science 375 , eabg9765 (2022) 21 January 2022 4 of 11 B D Time-lapse imaging reveals MultiFate-2.3 tristability High T ...
Zhuet al.,Science 375 , eabg9765 (2022) 21 January 2022 5 of 11 B External inducers switch cells between states A Modulating TF ...
Zhuet al.,Science 375 , eabg9765 (2022) 21 January 2022 6 of 11 Box 1. Design of the MultiFate circuit. Here we introduce the ma ...
Zhuet al.,Science 375 , eabg9765 (2022) 21 January 2022 7 of 11 2 3 4 5 6 7 8 9 10 11 Number of transcription factors (N) 101 10 ...
marker, into Chinese hamster ovary K1 (CHO- K1) cells and analyzed Citrine expression by flow cytometry 36 hours later (Fig. 2A ...
transferred back to the high-TMP media (Fig. 4A, bottom, and fig. S9). Thus, MultiFate’s ability to support irreversible transit ...
in a manner analogous to the stepwise expan- sion of MultiFate circuits demonstrated here ( 21 , 22 , 41 , 42 ). A remarkable fe ...
755 – 766 (2006). doi:10.1016/j.cell.2006.06.052; pmid: 16923394 T. Miyamotoet al., Myeloid or lymphoid promiscuity as a critic ...
GOLDOPENACCESS,DIGITAL,ANDFREETO ALLREADERS AsAAAS’s firstmultidisciplinary, openaccessjournal,ScienceAdvancespublishes research ...
RESEARCH ARTICLES ◥ ATTOSECOND SCIENCE Attosecond coherent electron motion in Auger-Meitner decay Siqi Li1,2†, Taran Driver1,3,4 ...
of the degenerate 2pelectrons participates in the decay, leading to excited cationic states. There is a small contribution from ...
electron emitted attiwill experience a mo- mentum shift in the direction ofA → ðÞti. Because the periodTLof the circularly polar ...
limit of this region is∼6.4 atomic units, and the upper limit extends to include all electrons at higher momenta. Equation 2 can ...
(G¼170 meV) was consistent with previous x-ray absorption measurements ( 27 ). The rela- tive amplitude between transitions to t ...
V. V. Serov, V. L. Derbov, T. A. Sergeeva, .Phys. Rev. A 87 , 063414 (2013). P. V. Demekhinet al.,J. Phys. At. Mol. Opt. Phys. ...
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