Science - USA (2022-02-04)
Schmidtet al.,Science 375 , eabj4008 (2022) 4 February 2022 6 of 12 IFNGIL2 No Targets Control DEPDC7DEF6 TAGAPRAC2 VAV1 Signali ...
cytokine gene expression, whereas positive regulators generally promoted more diverse cytokine expression patterns than negative ...
Biolabs, catalog no. E1602L). sgRNAs have been cloned into pXPR_502 (Addgene, catalog no. 96923) for CRISPRa and into CROPseq-Gu ...
than the other screens. To address this, addi- tional fixed cells from the same experiment were stained and sorted as an additio ...
(Luminex). To remove very lowly expressed cytokines for downstream analysis, any group in which three of four donors had undetec ...
trees shown were generated using the Seurat BuildClusterTreefunction with default argu- ments. For pseudobulk differential expre ...
C. Hafemeister, R. Satija, Normalization and variance stabilization of single-cell RNA-seq data using regularized negative bino ...
RESEARCH ARTICLE SUMMARY ◥ PLANT SCIENCE Natural historyÐguided omics reveals plant defensive chemistry against leafhopper pests ...
RESEARCH ARTICLE ◥ PLANT SCIENCE Natural historyÐguided omics reveals plant defensive chemistry against leafhopper pests Yuechen ...
NaJAZi, andNaJAZjnegatively correlated with theEmpoascanumbers and damage. The expression of JAZ genes known to me- diateM. sext ...
lines ofN. attenuataplants individually RNA interference (RNAi)–silenced [inverted repeat (ir)] or overexpressed (ov) in differe ...
Baiet al.,Science 375 , eabm2948 (2022) 4 February 2022 4of9 A 0 5 10 15 20 25 30 0 0.5 1 2 3 6 9 24 0 20 40 60 80 100 120 140 1 ...
RILs (data S2) and that seemingly minor differences in leaf sampling and extraction technique—potentially the simultaneous ex- p ...
involved in the regulation and biosynthesis of CP andm/z347.19, includingNaMYC2a,NaMYB8, andNaAT1, which encodes a hydroxycinnam ...
hexenal for a Michael addition reaction, the product of which is aromatized to form CPH (Fig. 4B). CPH is responsible forEmpoasc ...
Together, these in vitro and in vivo results suggest that CPH inN. attenuatais responsible for the plant’sEmpoascanonhost resist ...
MS/MS similarity scoring, biclustering, and molecular networking were used to iden- tify the unknownm/z347.19 metabolite. OS- in ...
Publishyourresearch intheSciencefamilyofjournals TheSciencefamilyofjournals(Science, Science Advances,ScienceImmunology, Science ...
RESEARCH ARTICLES ◥ MOLECULAR BIOLOGY Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolut ...
We constructed high-quality benchmark datasets for the machine learning model training. For 6mA negative controls, we used HEK-W ...
«
7
8
9
10
11
12
13
14
15
16
»
Free download pdf