Science - USA (2022-02-04)
hexenal for a Michael addition reaction, the product of which is aromatized to form CPH (Fig. 4B). CPH is responsible forEmpoasc ...
Together, these in vitro and in vivo results suggest that CPH inN. attenuatais responsible for the plant’sEmpoascanonhost resist ...
MS/MS similarity scoring, biclustering, and molecular networking were used to iden- tify the unknownm/z347.19 metabolite. OS- in ...
Publishyourresearch intheSciencefamilyofjournals TheSciencefamilyofjournals(Science, Science Advances,ScienceImmunology, Science ...
RESEARCH ARTICLES ◥ MOLECULAR BIOLOGY Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolut ...
We constructed high-quality benchmark datasets for the machine learning model training. For 6mA negative controls, we used HEK-W ...
SCIENCEscience.org 4 FEBRUARY 2022¥VOL 375 ISSUE 6580 517 Fig. 2. 6mASCOPE method evaluation.(A) IPD ratios (the mean IPD in the ...
6mA was enriched at the nucleosome-linker boundaries inC. reinhardtii(Fig. 3, A and D) instead of at the middle of the linkers, ...
674,650 SMRT CCS reads for single-molecule 6mA analysis (table S2). Despite strict mea- sures to avoid contamination ( 31 ), we ...
(fig. S12), Actinobacteria, Bacteroidetes, and Firmicutes. These phyla and classes (Fig. 4E and fig. S12) are consistent withA. ...
level estimates between 6mASCOPE and UHPLC- MS/MS (Fig. 5A) except theD. melanogaster embryo andA. thalianasamples, for which th ...
R. J. Roberts, T. Vincze, J. Posfai, D. Macelis,Nucleic Acids Res. 43 , D298–D299 (2015). D. S. Lundberget al.,Nature 488 , 86– ...
Replication and generalization Replication was performed on an admixed sample of 7410 individuals from UKB, includ- ing 2232 of ...
a significant heterogeneityP<1×10−^6 are listed in table S6. Comparison to previous cortical GWAS We used conditional and joi ...
SCIENCEscience.org 4 FEBRUARY 2022¥VOL 375 ISSUE 6580 525 Fig. 4. Three-dimensional genetic characterization of the cortex. (A) ...
were previously found to be associated with present-day humans compared to Neanderthal and Denisovan genomes ( 21 ). Perisylvian ...
with antagonistic effects (i.e., increasing area of one region while decreasing area of the other); these regions show good corr ...
Our results with genetically informed atlases demonstrate that human brain arealization and regionalization largely arise from p ...
understanding and quantitative account of crit- ical scaling functions remain elusive. Related issuesariseinawiderangeofstrongly ...
Fermi gas, in whichZ 2 andDLPturn out to be sizable near the superfluid transition ( 26 ). In Bragg spectroscopy ( 27 – 29 ), th ...
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