Small Animal Dermatology, 3rd edition

(Tina Sui) #1

788 APPENDIX B DRUG FORMULARY


Drug name (trade orother names)

Pharmacology andindications

Adverse effects andprecautions

Dosing information andcomments

Formulations

Dosage (unlessotherwise indicated,dose is the same fordogs and cat)

L-Lysine (Enisyl-F)

Amino acid for treatmentof herpes infections. Oralsupplementation for catswith feline herpesvirus-1(FHV-1) infection isassociated with reducedviral shedding.

Well tolerated in cats.

Doses listed will reduceviral shedding. Powdercan be mixed with food.Paste can be givendirectly.

250 mg/mL paste.

Cat: 400 mg po/day. Pasteformulation 1–2 mL po toadult cats and 1 mL tokittens.

Marbofloxacin(Zeniquin)

Fluoroquinoloneantimicrobial. Spectrumincludes staphylococci,gram-negative bacilli, andsome

Pseudomonas

.


May cause some nauseaand vomiting at highdoses. Avoid use in younganimals. Safe for cats(ocular safety) atrecommended dose.

Use susceptibility testingto guide therapy.

25, 50, 100, and200 mg tablets.

2.75–5.55 mg/kg q24hpo.

Maropitant (Cerenia)

Antiemetic. Neurokinin(NK) type-1 inhibitor.Maropitant acts toprevent vomiting causedby chemotherapy andmotion sickness. It is alsoeffective for inhibitingvomiting from bothcentral and peripheralstimulation.

In clinical trials, there werefew adverse effects indogs. Salivation andmuscle tremors occurredin some animals.

Studies have shown NK-1inhibitors to be effectiveantiemetics for a varietyof stimuli.

10 mg/mL injection;16, 24, 60, or160 mg tablets.

Dog: 1 mg/kg SC q24h forup to 5 days; 2 mg/kg poq24h for up to 5 days; formotion sickness, 8 mg/kgpo q24h for up to 2 days.Cat: dose not established.
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