Cell - 8 September 2016
Article Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation Graphical Abstract Highli ...
Article Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation Andrew Wang,1,2,7Sarah C. ...
or they can be unintended and detrimental but unavoidable con- sequences of infections. Furthermore, the physiological changes t ...
only glucose significantly increased mortality (Figure 2B). We then tested whether the effects of food intake on susceptibility ...
monitoring (body temperature, blood O 2 saturation, respiratory rate, and heart rate) in endotoxemic mice treated with PBS, gluc ...
of LPS mice given 2DG, compared to mice given LPS and PBS or glucose. Together, these data implicate neuronal dysfunction as a p ...
Figure 3. Caloric Supplementation and Glucose Utilization Is Required for Surviving Influenza Infection (A) Food consumption aft ...
to immunopathology in the hindbrain, downstream of IFNaR signaling. Lethal Effect of 2DG in Viral Inflammation Is Mediated by CH ...
Figure 5. Inhibition of Glucose Utilization in Poly(I:C)-Induced Inflammation Enhances ER Stress (A) WT andIfnar/mice were cha ...
Glucose Promotes Neuronal ROS and Seizure-Induced Death in Bacterial Inflammation Prolonged fasting results in hypoglycemia acco ...
Figure 6. Role of Ketogenic Program in Surviving Bacterial, but Not Viral, Inflammation (A) Plasma nonesterified fatty acids (NE ...
viral inflammation. Unexpectedly, we found that these effects on mortality were largely independent of the degree of inflammatio ...
mitigating tissue damage and mortality.Shimazu et al. (2013) recently reported that BHOB functioned as an HDAC-1 inhibitor and t ...
A video abstract is available athttp://dx.doi.org/10.1016/j.cell.2016.07. 026#mmc2. AUTHOR CONTRIBUTIONS A.W., S.C.H., and H.H.L ...
Li, M.V., Chen, W., Harmancey, R.N., Nuotio-Antar, A.M., Imamura, M., Saha, P., Taegtmeyer, H., and Chan, L. (2010). Glucose-6-p ...
STAR+METHODS KEY RESOURCES TABLE REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit polyclonal anti-bTubulin Santa Cruz Cat ...
CONTACT FOR REAGENT AND RESOURCE SHARING Further information and requests for reagents may be directed to, and will be fulfilled ...
Kidney (MDCK) cells and titrated to determine concentration by plaque assay described below. For influenza infection, mice were ...
L. monocytogenesgrowth in macrophages, titrated amounts of culture supernatant and cell lysate were plated on BHI plates and gro ...
Digital light microscopic images were acquired using a Zeiss Axio Imager A1 microscope, an AxioCam MRc5 Camera, and AxioVision 4 ...
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