548
Ubiquitin-proteasome pathway (cont.)
CPEB, 512
ELAVL2 elimination, 512
in eukaryotic cells, 511
F-box family of proteins, 511
GNF SymAtlas, 511
mammalian oocytes and early
embryos, 511
MG132, 511
mouse oocytes and zygotes, 511
multimeric ubiquitin-ligating protein (E3)
complex, 511
proteome dynamics, OET, 512–514
transcriptome profiling, 511
U-rich motifs, 504
Urodeles, 416, 417, 419–421
endoderm/mesoderm, 416
gastrula stages, 417
inductive, 417, 419–421
V
Vertebrate axial organization, 211
Vertebrate blastoderm. See Fate maps
Vertebrate embryology, 212, 265
animal–vegetal axis, 213
dorsal axis and bilateral symmetry, 214
gray crescent formation, 214
Vertebrate embryonic cleavage patterns
holoblastic cleavage, 119
meroblastic cleavage, 119
spindles, 124
Vertebrate germ cell specification, 385
Vertebrate germ layers, 357–361
Vg1/Nodal pathways, 55
Vogt’s fate map, 328
W
Wnt ligands, 55, 56
Wnt/beta-catenin signaling, 215, 219,
241–245
amniote axis formation
chick, 241–243
mouse, 242–245
Xenopus, 235–238
zebrafish, 237, 238
Wnt/planar cell polarity (PCP) signaling,
230–232
X
Xenopus, 398–399, 403
Bb, 396
cell cycle regulation, 408
germ line, 405–407
germ line mRNAs, 400–402
germ plasm formation
oocytes, 403
RNA localization, 398–399
Xenopus embryo, 399
GFM, 397
miR-functions, 410
Nanos, 403, 404
Oct60 and Oct25, 409
oocytes, 409
oogenesis, 408
PGCs, 407, 410
Piwi proteins, 410
RNA-binding protein Pumilio, 408
tailbud stages, 404
VegT, 409
Xvelo RNA, 397
Xenopus Emi1-related protein 1 (XErp1), 90,
97, 104, 105
Xenopus laevis, 52–59, (see also
Embryogenesis)
egg extract, 92
embryonic development
embryonic asymmetries, 52, 53
germ layers, 53
maternal mRNA
biological functions, 53–54
germ layers and embryonic
asymmetries, 54, 55
maternal stages, 50
oogenesis and oocyte maturation, 50–52
regulated translation
CPE/CPEB-dependent polyadenylation
and translation, 59
mRNA polyadenylation, 58
musashi-dependent polyadenylation, 59
signaling pathways, 55
BMP, 56
FGF, 56
Vg1/Nodal pathways, 56, 57
Wnt, 56
translational control, 60
Y
Yolk consumption, 520–521
Yolk syncytial layer (YSL), 177
Z
Zebrafish, 386–389, 391–395
embryonic development, 385
genetic approaches, 395
genetic model, 385
Index