Imaging in Stem Cell Transplant and Cell-based Therapy
11 based metalloproteins for MR imaging has its own drawbacks, especially related to toxicity from iron accumulation [ 22 ]. The ...
12 in combination with oxygen, magnesium and ATP results in a reddish light (500–700 nm). On the other hand, fluorescent techniq ...
13 Deoxyglucose) are positron emitters and decay by emitting high-energy gamma rays that need a PET scanner to generate images. ...
14 stem cells have been studied using this approach including myocardial stem cell (Fig. 1.4) [ 32 ], pancreatic islet cells [ 3 ...
15 Kraitchman DL, Bulte JWM. Imaging of stem cells using MRI. Basic Res Cardiol. 2008; 103(2):105–13. Modo M, Cash D, Mellodew ...
© Springer International Publishing AG 2017 17 T. Pandey (ed.), Imaging in Stem Cell Transplant and Cell-based Therapy, Stem Cel ...
18 2.1 Introduction While the introduction of stem cell-based therapies has significantly widened the horizons of regenerative m ...
19 agriculture, household goods, cosmetics, textiles, heavy industry, and more [ 4 ]. Nanomedicine is one of the leading fields ...
20 2.3 Tracking of Nanoparticles In Vivo The common techniques of imaging of stem cells in vivo have been covered else- where in ...
21 nanoparticle called Gado CELLTrack™ to locate, track and quantify implanted cells in in vivo using MRI, and thus far this is ...
22 nanoparticles, served as high contrast agents, aiding in PAI of targeted cells [ 31 ]. Particularly, tunable near-infrared (N ...
23 for clinical use as liver-specific contrast agents—however, the production of both has since been ceased due to commercial re ...
24 cases MRI detection requires clusters of thousands of labeled cells [ 47 ], and this becomes problematic as extensive in vivo ...
25 2.4.3 Silica Nanoparticles Silica nanoparticles do not have autofluorescence, but rather act as a matrix to chemically and ph ...
26 2.4.4 Polymer Nanoparticles Polymer nanoparticles can be used in stem cell tracking when conjugated with fluo- rescent organi ...
27 2.4.5 Gold Nanoparticles Gold nanoparticles (Fig. 2.7) have several properties that make them a promising agent for stem cell ...
28 spectrometry analysis [ 24 , 25 ]. In vitro studies have shown that mesenchymal and adipose-derived stem cells labeled with g ...
29 been reported to engineer nanoparticles and their architectures with desirable size, shape, and functionality, including thos ...
30 2.6 General Safety Due to exponentially growing numbers of suggested nanotechnology applications, a branch of science has bee ...
31 2.7 Conclusions With over 2000 clinical trials involving stem cells underway, it is critical that meth- ods to deliver and tr ...
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